Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT07464262

Telemonitoring With CPAP in Severe Obstructive Sleep Apnea in Primary Health Care

Led by Federal University of São Paulo · Updated on 2026-03-11

200

Participants Needed

1

Research Sites

90 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Obstructive sleep apnea (OSA) is a prevalent sleep disorder associated with cardiovascular, metabolic, cognitive, and psychological complications. Continuous Positive Airway Pressure (CPAP) therapy is the gold standard treatment for moderate to severe OSA; however, long-term adherence remains a major challenge, particularly in real-world primary care settings. This study aims to evaluate the effectiveness of telemonitoring using CPAP devices in improving treatment adherence and clinical outcomes among patients with severe OSA receiving care within the Brazilian Primary Health Care system. This randomized controlled trial will include 200 adult participants with severe OSA who are new users of CPAP therapy and are followed by primary health care units in the Southeast Regional Health Coordination of São Paulo, Brazil. Participants will be randomly allocated into two groups: a telemonitoring intervention group, monitored remotely through the AirView® platform and the myAir® application, and a control group receiving standard care without telemonitoring. Primary outcomes include CPAP adherence and residual apnea-hypopnea index (AHI). Secondary outcomes include daytime sleepiness, sleep quality, mood, cognitive complaints, and patient perceptions of care. Quantitative clinical data will be collected through CPAP telemonitoring systems and standardized questionnaires, while qualitative data will be obtained through semi-structured interviews with patients and health professionals. The results of this study may provide evidence supporting the integration of digital health technologies into primary health care services to improve adherence to CPAP therapy and optimize the management of obstructive sleep apnea in public health systems.

CONDITIONS

Official Title

Telemonitoring With CPAP in Severe Obstructive Sleep Apnea in Primary Health Care

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 75 years
  • Diagnosis of severe obstructive sleep apnea with apnea-hypopnea index of 30 or more events per hour
  • New users of CPAP therapy within 30 days of starting treatment
  • Resident in the Southeast Regional Health Coordination area of Sao Paulo, Brazil
  • Able to understand and sign informed consent
Not Eligible

You will not qualify if you...

  • Previous CPAP use longer than 30 days before enrollment
  • Need for bilevel ventilation or non-invasive ventilation due to hypoventilation syndromes, chronic hypercapnic COPD, or neuromuscular diseases
  • Predominant central sleep apnea (50% or more central events) or Cheyne-Stokes respiration
  • Recent unstable or severe health problems such as decompensated heart failure, recent heart attack, or stroke within 3 months
  • Severe cognitive impairment or psychiatric disorder preventing study understanding or adherence
  • Conditions preventing safe use of CPAP mask like major facial deformities or trauma
  • Unable to maintain follow-up in primary care services of Southeast Regional Health Coordination
  • Participation in another interventional clinical trial that could affect study results

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Primary Health Care Units - Southeast Regional Health Coordination

São Paulo, São Paulo, Brazil, 04023-062

Actively Recruiting

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Research Team

A

Andre Morente, PharmD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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