Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
NCT05082181

Telephone-Based Support Programs for People With Epilepsy

Led by NYU Langone Health · Updated on 2026-02-17

120

Participants Needed

1

Research Sites

303 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a two-arm randomized controlled trial to compare telephone-based depression self-management (UPLIFT) to telephone-based support groups (BOOST). A sample of 120 English- and Spanish-speaking people with epilepsy (PWE) with elevated depressive symptoms will be enrolled. Both interventions are 8-week programs delivered in one-hour weekly sessions to groups of about 6 participants. Changes in depressive symptoms, quality of life and seizures will be assessed over 12 months. The trial will also examine mediators and moderators of treatment effects.

CONDITIONS

Official Title

Telephone-Based Support Programs for People With Epilepsy

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults 18 years of age or older
  • Diagnosed with epilepsy for at least one year
  • Fluent in English or Spanish
  • Elevated depressive symptoms with PHQ-9 score 10 or higher
  • Willing to participate in audiotaped group telephone sessions
Not Eligible

You will not qualify if you...

  • Severe depressive symptoms with PHQ-9 score 20 or higher
  • Active suicidal ideation (PHQ-9 item #9 score 1 or more or reported during screening)
  • Active psychotic disorder based on psychiatric diagnosis or antipsychotic medication use
  • Significant cognitive impairment noted in medical records or during screening

AI-Screening

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Trial Site Locations

Total: 1 location

1

NYU Langone Health

New York, New York, United States, 10016

Actively Recruiting

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Research Team

T

Tanya Spruill, PhD

CONTACT

A

Alexis Bartelloni, MSPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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