Actively Recruiting

Phase Not Applicable
Age: 21Years - 80Years
All Genders
NCT04682223

Telerehabilitation for Aphasia (TERRA)

Led by University of South Carolina · Updated on 2026-04-02

100

Participants Needed

1

Research Sites

303 weeks

Total Duration

On this page

Sponsors

U

University of South Carolina

Lead Sponsor

N

National Institute on Deafness and Other Communication Disorders (NIDCD)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Speech-language therapy is generally found to be helpful in the rehabilitation of aphasia. However, not all patients with aphasia have access to adequate treatment to maximize their recovery. The goal of this project is to compare the efficacy of telerehabilitation or Aphasia Remote Therapy (ART) to the more traditional In-Clinic Therapy (I-CT).

CONDITIONS

Official Title

Telerehabilitation for Aphasia (TERRA)

Who Can Participate

Age: 21Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must have sustained a left hemisphere ischemic or hemorrhagic stroke at least 12 months prior to enrollment.
  • Participants must primarily speak English for at least the past 20 years.
  • Participants must be capable of giving informed consent or indicating another to provide informed consent.
  • Participants must be between 21-80 years of age.
  • Participants must be magnetic resonance imaging (MRI) compatible (e.g., no metal implants, not claustrophobic) on a 3-Tesla (3T) scanner.
Not Eligible

You will not qualify if you...

  • Participants must not have previous neurological disease affecting the brain (e.g. history of traumatic brain injury).
  • Participants must not have severely limited speech production (severe unintelligibility) and/or auditory comprehension that interferes with adequate participation in the therapy provided (i.e., WAB-R Spontaneous Speech rating scale score of 0-1 or WAB-R Comprehension score of 0-1).
  • Participants must not have a history of stroke to the right hemisphere of the brain.
  • Participants must not have a bilateral, cerebellar or brainstem stroke.
  • Participants must not have anything that makes them be 3T MRI incompatible.
  • Insufficient intelligible speech to provide accurate responses with discourse/naming.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

University of South Carolina Aphasia Lab

Columbia, South Carolina, United States, 29201

Actively Recruiting

Loading map...

Research Team

S

Sara Sayers, M.S.

CONTACT

K

Kelli Powell, B.S.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here