What is telerehabilitation studying for stroke recovery?

Telerehabilitation is being studied to see if adding it to usual care improves arm movement and reduces disability after stroke. This study evaluates whether remote therapy sessions focused on arm exercises can help patients recover better than usual care alone. The University of California, Los Angeles is leading this research.

Who may be eligible for this stroke clinical trial?

Adults aged 18 to 80 years with arm weakness caused by a stroke that happened 90 to 150 days ago may be eligible. Participants must be able to follow simple commands and willing to complete all study visits. Please review eligibility criteria for more details.

Is there any cost to participate in this stroke clinical trial?

Study-related care, including the study treatment and all trial visits, is provided at no cost. However, personal travel expenses may vary and are not guaranteed to be covered. Participants should plan accordingly for any travel costs.

Actively Recruiting

Phase Not Applicable

Age: 18Years - 80Years

All Genders

ID06682429

Home-Based Telerehabilitation Combined With Usual Care to Improve Arm Function After Stroke in Adults Aged 18 to 80

Led by University of California, Los Angeles · Updated on 2026-08-04

202

Participants Needed

Research Sites

52 weeks

Total Duration

AI-Summary

What this Trial Is About

This research study is focused on people who have arm weakness due to a stroke that occurred 90 to 150 days earlier. The study aims to find out if adding telerehabilitation TR to usual care can improve arm function and reduce overall disability better than usual care alone. It is a randomized, controlled, and assessor-blinded trial evaluating this treatment approach for stroke recovery. Participants will be randomly assigned to either receive telerehabilitation plus their usual care or to continue with usual care alone. The telerehabilitation involves 70 minutes per day of arm-targeted activities, including exercises, games, and stroke education, for 6 days a week over 6 to 8 weeks. Half of these sessions are supervised remotely by licensed therapists via videoconferencing, while the other half are completed independently. The usual care group will be offered telerehabilitation after the study ends. The study lasts about 8 months and includes 4 in-person visits during which various assessments are performed, including arm function tests and one MRI brain scan. Researchers will measure changes in arm function using the Action Research Arm Test and examine disability with the modified Rankin Scale. Participants progress and safety will be monitored throughout, and the study will evaluate how telerehabilitation impacts recovery after stroke.

CONDITIONS

Brief Title

Telerehabilitation In The Home After Stroke

Who Can Participate

Age: 18Years - 80Years

All Genders

Eligibility Criteria

You may qualify if you...

Age 18-80 years at the time of randomization
Stroke confirmed by imaging due to ischemia or intracerebral hemorrhage, occurring 120±30 days before randomization
Upper arm weakness with Action Research Arm Test score between 18 and 44 at baseline
Box & Block Test score of at least 1 block in 60 seconds with affected arm at baseline
Able to perform all 3 example rehabilitation exercises (simple commands) at baseline
Provided informed consent and signed a behavioral contract personally

You will not qualify if you...

Major active neurological, psychiatric, or medical disease that may prevent compliance
Unable or unwilling to perform study procedures or therapy, or expected noncompliance
Another diagnosis affecting the weakened arm function besides the stroke
Severe depression with Geriatric Depression Scale score over 10 at baseline
Significant cognitive impairment with Montreal Cognitive Assessment score below 22 (except for aphasia cases approved by site PI)
Communication deficits that interfere with study participation
Severe upper extremity spasticity with contracture or Ashworth Scale score of 4 in biceps or pectoralis
Modified Rankin Scale score above 2 before the stroke
New symptomatic stroke since the index stroke or another stroke within 30 days before the index stroke
Visual acuity worse than 20/50 in both eyes
Life expectancy less than 9 months
Pregnant or women of child-bearing potential without a negative pregnancy test
Botulinum toxin treatment to the affected arm in the past 3 months or expected during the study
Concurrent enrollment in another therapy-based investigational study overlapping with this one
Insufficient English or Spanish language skills to follow procedures and instructions
No stable home address within 1.5-hour drive of the study site during therapy period (can be waived by site PI)
Contraindication to MRI
On isolation precautions such as for active COVID-19

Research Team

Steven Cramer, MD

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Home-Based Telerehabilitation Combined With Usual Care to Improve Arm Function After Stroke in Adults Aged 18 to 80

On this page

AI-Summary

What this Trial Is About

Brief Title

Who Can Participate

Eligibility Criteria

Research Team

Not the Right Trial for You?

On this page

Who Can Participate

Eligibility Criteria