Actively Recruiting
Temporal Interference for Thalamocortical Activity and Network Modulation
Led by University of Wisconsin, Madison · Updated on 2026-04-22
40
Participants Needed
1
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to find out whether a type of electrical brain stimulation, called temporal interference stimulation, can temporarily change the way different parts of the brain communicate with each other. Participants will: * Complete two stimulation phases - overnight and during wakefulness * Undergo two MRIs per study phase
CONDITIONS
Official Title
Temporal Interference for Thalamocortical Activity and Network Modulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18-50
- Medically healthy
- U.S. citizen or permanent resident
- English-speaking
You will not qualify if you...
- Current or past neurological disorders or acquired neurological disease, including intracranial lesions
- History of inpatient psychiatric hospitalization
- Head trauma with prolonged loss of consciousness or more than three grade I concussions
- Poorly controlled headaches or migraines
- Systemic illness or unstable medical condition that may cause emergency with provoked seizure
- History of seizures, epilepsy, abnormal EEG, or family history of treatment resistant epilepsy (except single benign seizure)
- Possible pregnancy or plan to become pregnant in next 6 months
- Any metal in the head
- Medical devices or implants such as pacemakers, pumps, cochlear implants, or nerve stimulators
- Dental implants or permanent retainers
- Hair braids, dreadlocks, hair pieces, or extensions that cannot be removed before study
- Unwillingness to remove head coverings for study sessions
- Medications that may alter seizure threshold including specific stimulants, antidepressants, SSRIs, antipsychotics, bronchodilators, antibiotics, antivirals, antihistamines, or estradiol-based birth control
- Claustrophobia
- Back problems preventing lying flat for up to two hours
- Regular night-shift work
- Sleep apnea or other sleep disorder
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Wisconsin - Madison
Madison, Wisconsin, United States, 53705
Actively Recruiting
Research Team
S
Sean Prahl
CONTACT
L
Larissa Albantakis, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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