Actively Recruiting
Temporal Memory in Schizophrenic Patients
Led by Xiaofeng Ma · Updated on 2024-08-20
75
Participants Needed
1
Research Sites
6 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Temporal order memory deficits are a central feature of cognitive abnormalities in schizophrenia. The dorsolateral prefrontal cortex contributes to the extraction of temporal contextual information. Transcranial direct current stimulation (tDCS) and interim testing have been shown to be external techniques that can improve temporal order memory deficits in schizophrenia patients. Transcranial alternating current stimulation (tACS) can also improve cognitive functioning in patients with schizophrenia. This study intends to investigate the learning effects of temporal order memory under two learning strategies during tDCS targeting the left dorsolateral prefrontal cortex (L-DLPFC) and transcranial direct current stimulation (tDCS) interventions in patients with schizophrenia, to investigate whether it can promote the retention of temporal order memory in patients, and to compare the differences in the effects of the two intervention modalities. This study was planned to recruit 75 patients diagnosed with schizophrenia from the hospital. A single online tDCS (2 mA × 20 min) and tACS (1.5 mA × 20 min, theta rhythm) intervention was conducted during which participants performed a temporal-sequence memory task for visual pictures, and test scores were compared for each stimulus type on an intermediate test and repetition of the two strategies of learning.
CONDITIONS
Official Title
Temporal Memory in Schizophrenic Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of schizophrenia according to DSM-5 criteria
- Age 18 years or older, any gender, with at least elementary school education
- Receiving stable antipsychotic treatment and in a stable phase of illness
- Ability to understand and cooperate with testing requirements
- No history of neurological disorders, serious physical illnesses, or intellectual disability
- Normal or corrected vision with no color blindness or color vision impairments
You will not qualify if you...
- Presence of cognitive impairment due to somatic or brain organic lesions like cerebrovascular disease or traumatic brain injury
- Mental disorders caused by substance dependence or abuse or psychoactive substance use
- History of brain injury or central nervous system organic diseases
- Significant risk of suicide or harm to others
- Participation in similar experiments within 30 days before baseline
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Northwest Normal University
Lanzhou, Gansu, China, 730070
Actively Recruiting
Research Team
T
Tiantian Li, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here