Actively Recruiting

Age: 60Years +
All Genders
Healthy Volunteers
NCT05372172

Tennessee Alzheimer's Project

Led by Vanderbilt University Medical Center · Updated on 2026-02-05

1000

Participants Needed

1

Research Sites

439 weeks

Total Duration

On this page

Sponsors

V

Vanderbilt University Medical Center

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Core will create an infrastructure to support research efforts of both local and national investigator studies to develop early detection, prevention, and treatment strategies for Alzheimer's disease. The Clinical Core intends to enroll up to 1000 participants, including individuals who are cognitively unimpaired, have mild cognitive impairment, or have Alzheimer's disease. This cohort of about 1000 participants will be called the Tennessee Alzheimer's Project. Participants will be seen annually for comprehensive clinical characterization and then referred to other studies to enhance Alzheimer's disease research activities.

CONDITIONS

Official Title

Tennessee Alzheimer's Project

Who Can Participate

Age: 60Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 60 or older
  • Meet standard criteria for cognitively unimpaired, mild cognitive impairment, or Alzheimer's disease
  • English speaking
  • Individuals must be able to provide informed consent at baseline (no lack of decisional capacity)
Not Eligible

You will not qualify if you...

  • No available reliable study partner who interacts significantly and can join study visits
  • History of major psychiatric illness such as schizophrenia or bipolar disorder
  • History of neurological illness such as epilepsy, multiple sclerosis, or Parkinson's disease
  • History of head injury with significant loss of consciousness
  • Unable to undergo MRI due to claustrophobia or presence of ferrous metal in body

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37232

Actively Recruiting

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Research Team

M

Michelle Houston

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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