Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT06646913

TENS in Scleroderma

Led by University of Michigan · Updated on 2025-07-03

16

Participants Needed

1

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this pilot study is to assess the acceptability of the transcutaneous electrical acustimulation (TEA) device in treating Scleroderma-related gastroparesis. The main objective is: To evaluate the acceptability of TEA as an intervention for alleviating symptoms of distension and bloating in individuals diagnosed with Scleroderma. Participants will be provided with the TEA devices that will be applied to the skin for a total of 45 minutes twice daily after meals. Participants will be asked to fill out both daily diaries and biweekly questionnaires to assess for improvement in the gastroparesis symptoms. Participants will also be asked to complete the daily diaries in addition weekly questionnaires during a 4 week post-treatment follow-up period.

CONDITIONS

Official Title

TENS in Scleroderma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Systemic Sclerosis according to the 2013 American College of Rheumatology and European League against Rheumatism criteria
  • Age 18 years or older
  • English speaking
  • Moderate to severe symptoms of distension or bloating reported on the UCLA Scleroderma Clinical Trials Consortium Gastrointestinal Tract Instrument 2.0
  • Stable gastrointestinal therapy including prokinetics for at least 4 weeks prior
Not Eligible

You will not qualify if you...

  • Pregnant or currently breastfeeding
  • History of major abdominal surgery (except cholecystectomy, appendectomy, or surgery deemed non-major by investigators)
  • Active disorders causing abdominal pain unrelated to Scleroderma, such as inflammatory bowel disease, diabetes, or unstable thyroid disease
  • Known allergy to adhesive ECG electrodes
  • Known contraindications to transcutaneous electrical acustimulation, including having a cardiac pacemaker or epilepsy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Michigan

Ann Arbor, Michigan, United States, 48912

Actively Recruiting

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Research Team

D

Dinesh Khanna, MD, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DEVICE_FEASIBILITY

Number of Arms

1

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TENS in Scleroderma | DecenTrialz