Actively Recruiting
Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury
Led by Johns Hopkins University · Updated on 2025-11-12
36
Participants Needed
1
Research Sites
495 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this clinical trial is to evaluate the efficacy of tesamorelin as a therapy for peripheral nerve injuries. The investigators hypothesize that treatment with tesamorelin will result in faster and more substantial recovery of motor and sensory function following surgical repair of injured peripheral nerves. Patients with upper extremity nerve injuries will be randomly assigned to receive either tesamorelin treatment or no treatment. Assessments for nerve regeneration, muscle function, and sensation will be conducted every three months for a total of 12 months. Outcomes in patients receiving tesamorelin will be compared to those in the untreated group to determine the effectiveness of tesamorelin as a therapeutic intervention for nerve injuries.
CONDITIONS
Official Title
Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ulnar nerve laceration at the wrist that has been repaired primarily
You will not qualify if you...
- Active or past certain cancers
- Uncontrolled diabetes or hypertension
- Certain pituitary disorders
- Use of oral contraceptives
- Pregnancy
- Drug or alcohol dependence
- Psychosocial issues that would limit participation and compliance
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sami Tuffaha
Baltimore, Maryland, United States, 21205
Actively Recruiting
Research Team
S
Sami Tuffaha, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here