Actively Recruiting
Tessa Jowell BRAIN MATRIX - Platform Study
Led by University of Birmingham · Updated on 2026-05-05
1000
Participants Needed
14
Research Sites
375 weeks
Total Duration
On this page
Sponsors
U
University of Birmingham
Lead Sponsor
T
The Brain Tumour Charity
Collaborating Sponsor
AI-Summary
What this Trial Is About
The main aim of the Tessa Jowell BRAIN MATRIX - Platform Study is to more precisely determine the exact type of tumour patients have by developing the essential infrastructure to provide rapid and accurate molecular diagnosis. A large network of clinical hubs across the United Kingdom, with expertise in managing patients with brain tumours, will be developed. Once established this infrastructure will facilitate the rapid introduction of clinical trials testing targeted therapies tailored to the genetic changes of an individual's tumour.
CONDITIONS
Official Title
Tessa Jowell BRAIN MATRIX - Platform Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Newly diagnosed suspected WHO Grade 2-4 glioma confirmed by imaging and suitable for surgery to obtain tumour and blood samples
- Patients with progression of known WHO Grade 2-4 glioma, prioritizing those with frozen tumour samples available
- Valid written informed consent provided for the study
You will not qualify if you...
- Primary spinal cord tumours
- Active treatment for other cancers
- Contraindications to MRI
- Lack of standard of care imaging available
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 14 locations
1
Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust
Birmingham, United Kingdom, B15 2TH
Actively Recruiting
2
Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust
Cambridge, United Kingdom, CB2 0QQ
Terminated
3
Velindre Cancer Centre, Velindre University NHS Trust
Cardiff, United Kingdom, CF14 2TL
Actively Recruiting
4
NHS Lothian
Edinburgh, United Kingdom, EH4 2XU
Active, Not Recruiting
5
Queen Elizabeth Unviersity Hospital, NHS Greater Glasgow and Clyde Health Board
Glasgow, United Kingdom, G51 4TF
Active, Not Recruiting
6
St James's University Hospital, Leeds Teaching Hospitals NHS Trust
Leeds, United Kingdom, LS9 7TF
Actively Recruiting
7
The Walton Centre, The Walton Centre NHS Foundation Trust
Liverpool, United Kingdom, L9 7LJ
Actively Recruiting
8
King's College Hospital, King's College Hospital NHS Foundation Trust
London, United Kingdom, SE5 9RS
Actively Recruiting
9
Charing Cross Hospital, Imperial College Healthcare NHS Trust
London, United Kingdom, W6 8RF
Actively Recruiting
10
The Christie Hospital, The Christie NHS Foundation Trust
Manchester, United Kingdom, M20 4BX
Actively Recruiting
11
Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust
Manchester, United Kingdom, M6 8HD
Actively Recruiting
12
Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust
Newcastle upon Tyne, United Kingdom, NE7 7DN
Actively Recruiting
13
Queen's Medical Centre, Nottingham University Hospitals NHS Trust
Nottingham, United Kingdom, NG7 2UH
Actively Recruiting
14
Churchill Hospital, Oxford University Hospitals NHS Foundation Trust
Oxford, United Kingdom, OX3 9DU
Actively Recruiting
Research Team
R
Rhys Mant
CONTACT
J
Joshua Savage
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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