Actively Recruiting
Test of Target Engagement of Ambiguity Aversion
Led by Northwestern University · Updated on 2025-11-21
140
Participants Needed
1
Research Sites
234 weeks
Total Duration
On this page
Sponsors
N
Northwestern University
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The present work aims to test whether a single session intervention alters ambiguity aversion, both in terms of people's decision making and their brain responses to ambiguous choices.
CONDITIONS
Official Title
Test of Target Engagement of Ambiguity Aversion
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 25 to 60
- Right-handed
- Ability to read and write English
- Capacity to provide informed consent
- Intolerance of uncertainty score at or above 31st percentile (≥ -0.5 standard deviation below the mean)
You will not qualify if you...
- Personal history of psychosis, mania, or hypomania
- Personal history of autism spectrum disorder
- IQ below 80 as determined by the Wechsler Test of Adult Reading
- Head injury with loss of consciousness lasting more than 120 seconds
- Neurological conditions such as epilepsy, Parkinson's disease, cerebral palsy, or history of stroke
- Currently pregnant
- Use of any implanted electrical device such as pacemaker, spinal stimulator, vagal nerve stimulator, or Inspire sleep apnea device
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
Research Team
B
Brent I Rappaport, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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