Actively Recruiting

Phase Not Applicable
Age: 0Years - 17Years
MALE
NCT02872532

Testicular Tissue Cryopreservation in Children

Led by Mayo Clinic · Updated on 2025-12-08

200

Participants Needed

1

Research Sites

745 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This protocol is being designed to offer testicular tissue cryopreservation to male pediatric patients (0-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may cause loss of reproductive potential.

CONDITIONS

Official Title

Testicular Tissue Cryopreservation in Children

Who Can Participate

Age: 0Years - 17Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Be male and aged 0 to 17 years
  • Scheduled to undergo surgery, chemotherapy, drug treatment, and/or radiation with a high or intermediate risk of causing permanent and complete loss of testicular function
  • Have a medical condition or malignancy requiring removal of all or part of one or both testicles
  • Have a genetic or autoimmune medical condition that results in declining fertility (e.g., Klinefelter syndrome)
  • Have a newly diagnosed or recurrent disease affecting fertility without prior therapy likely causing permanent testicular failure
  • Have two testicles if undergoing elective removal of one testicle for fertility preservation, or have one testicle with limited fertility potential and no other preservation options
  • Provide informed consent and authorization for specimen collection and release of personal health information
  • Consent to serum screening tests for infectious diseases at the time of tissue harvesting
  • Undergo full history, physical examination, and standard pre-operative clearance as determined by their primary surgeon
  • Patients with testicular torsion or other conditions impairing testicular function may be included if viable tissue is found during surgery
Not Eligible

You will not qualify if you...

  • Have psychological, psychiatric, or other conditions preventing fully informed consent
  • Have an underlying medical condition that significantly increases risk from anesthesia and surgery
  • Previously received gonadotoxic chemotherapy or radiation therapy resulting in impaired testicular function

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

A

Asma Chattha, MBBS

CONTACT

C

Chloe Schluttner

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Testicular Tissue Cryopreservation in Children | DecenTrialz