Actively Recruiting
Testing Adaptive Interventions to Improve Posttraumatic Stress Disorder Treatment Outcomes in Federally Qualified Health Centers
Led by University of Michigan · Updated on 2025-08-14
430
Participants Needed
13
Research Sites
201 weeks
Total Duration
On this page
Sponsors
U
University of Michigan
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This trial is being completed to develop a stepped-care talk therapy model for patients with PTSD. Specifically, this study is testing whether beginning with one type of therapy is better than beginning with another type of therapy, and whether moving to a different therapy after four sessions is more helpful than staying with the same therapy, depending on how well it is working. The central hypothesis is that beginning with a low- or medium-intensity PTSD intervention and then titrating intensity based on early indications of response will result in clinically significant PTSD symptom reduction with parsimony of resources.
CONDITIONS
Official Title
Testing Adaptive Interventions to Improve Posttraumatic Stress Disorder Treatment Outcomes in Federally Qualified Health Centers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Receive care at a participating federally qualified health center (FQHC)
- Have a Posttraumatic Stress Disorder checklist (PCL-5) score greater or equal (≥) to 33
- Own a mobile device that can be used for the PTSD Coach App
- Have had psychotropic medication stability for at least 4 weeks
You will not qualify if you...
- Severe cognitive impairment that makes adherence to the study regimen unlikely
- High risk of suicide as defined by meeting criteria for Action Step 3 on the Participant Suicide Risk Screening form
- Severe alcohol or substance use disorder (AUDIT score ≥ 15 or high risk on National Institute on Drug Abuse Quick Screen with score ≥ 27)
- Active psychosis or unmanaged bipolar disorder
- Unstable housing
- Current engagement in a trauma-focused behavioral treatment such as Prolonged Exposure or Cognitive Processing Therapy
- Patients who do not speak English will be excluded for logistical reasons
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 13 locations
1
Family Health Care
Baldwin, Michigan, United States, 49304
Terminated
2
Grace Health
Battle Creek, Michigan, United States, 49037
Actively Recruiting
3
Genesee Community Health Center
Flint, Michigan, United States, 48503
Actively Recruiting
4
Hamilton Community Health Network
Flint, Michigan, United States, 48503
Actively Recruiting
5
Cherry Health
Grand Rapids, Michigan, United States, 49503
Actively Recruiting
6
MidMichigan Community Health Services
Houghton Lake, Michigan, United States, 48629
Actively Recruiting
7
Upper Great Lakes Family Health Care Center
Menominee, Michigan, United States, 49858
Actively Recruiting
8
Family Medical Center of Michigan
Monroe, Michigan, United States, 48162
Actively Recruiting
9
Sterling Area Health Center
Sterling, Michigan, United States, 48659
Actively Recruiting
10
Family Care Health Centers
St Louis, Missouri, United States, 63111
Actively Recruiting
11
Western North Carolina Community Health Services
Asheville, North Carolina, United States, 28801
Actively Recruiting
12
CommUnityCare Health Centers
Austin, Texas, United States, 78702
Actively Recruiting
13
Unity Care NW
Bellingham, Washington, United States, 98225
Actively Recruiting
Research Team
K
Kayla Longuski, MS
CONTACT
H
Heather Walters
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
6
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