Actively Recruiting
Testing the Contribution of Orbitofrontal Cortex Networks to Decision-making
Led by Northwestern University · Updated on 2024-08-19
120
Participants Needed
1
Research Sites
215 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research study examines the contribution of orbitofrontal cortex (OFC) networks to decision-making.
CONDITIONS
Official Title
Testing the Contribution of Orbitofrontal Cortex Networks to Decision-making
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 40 years old
- Right-handed
- Fluent English speakers
You will not qualify if you...
- History of significant neurological conditions such as epilepsy, dementia, multiple sclerosis, or brain tumors
- History of major psychiatric conditions including general anxiety disorder, depression, schizophrenia, obsessive-compulsive disorder, post-traumatic stress disorder, attention deficit hyperactivity disorder, or substance use disorder
- Significant medical illnesses like cancer, meningitis, chronic obstructive pulmonary disease, or cardiovascular disease
- Significant cerebrovascular risk factors including hypertension, diabetes, or elevated cholesterol
- Current use of psychoactive medications such as barbiturates, benzodiazepines, chloral hydrate, haloperidol, lithium, carbamazepine, phenytoin, citalopram, escitalopram, fluoxetine, or diazepam
- Smell or taste dysfunction
- History of significant allergies requiring hospitalization
- History of severe asthma requiring hospitalization
- Habitual smoking
- History of eating disorders including anorexia nervosa, bulimia nervosa, or binge-eating disorder
- Dieting or fasting
- Presence of magnetic implants like shunts, stents, aneurysm clips, surgical clips, cochlear implants, or metal bone/joint hardware
- Presence of electronic implanted devices such as cardiac defibrillators, pacemakers, deep brain or spinal cord stimulators, internal electrodes, or medication infusion devices
- History of metal working without proper eye protection or injury with metal shrapnel
- Claustrophobia
- Pregnancy
- Predisposition to seizures including personal or family history, alcoholism, or pregnancy
- Use of medications that increase seizure risk such as bupropion SR, citalopram, duloxetine, ketamine, or gamma-hydroxybutyrate
- History of brain or spinal cord surgery
- History of severe head trauma with loss of consciousness
- History of fainting spells or syncope
- Hearing problems or tinnitus
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Northwestern University
Chicago, Illinois, United States, 60657
Actively Recruiting
Research Team
C
Christina Zelano, PhD
CONTACT
G
Greg Lane, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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