Actively Recruiting
Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors
Led by Massachusetts General Hospital · Updated on 2026-03-06
150
Participants Needed
2
Research Sites
59 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to test if Savvy, a multimodal intervention (consisting of psychological exercises, a weekly pill organizer, and a text message reminder system) can improve medication adherence in stroke survivors. The main questions it aims to answer are: * Can the Savvy tool improve medication adherence in stroke survivors compared to usual care? * Does the use of the Savvy tool lead to better blood pressure control after a stroke? The investigators will compare the use of the Savvy intervention to a control group that receives usual care, including a package of educational materials. The study consists of the following components: * Participants will receive the Savvy intervention or usual care. The intervention package consists of short psychological exercises over the phone, a weekly medication organizer to support daily medication intake, and text message reminders to take medication and refill the medication box. Participants in the control group will receive usual care, including educational materials about the importance of blood pressure and medication. * All participants will receive a free home blood pressure monitor and will be requested to measure their blood pressure at certain time points during the study. * Participants will be enrolled in the study for 6 months and will have virtual follow-up calls at 3 and 6 months.
CONDITIONS
Official Title
Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged 18 to 99 years at consent
- Self-reported stroke diagnosis (ischemic or hemorrhagic) within the past 12 months without traumatic or secondary causes
- Currently prescribed an antihypertensive medication
- Medication adherence below optimal level, indicated by a Medication Adherence Report Scale score less than 25
- Cognitively able to manage medications independently, with Six-Item Screener score above 4
- English-speaking to complete consent and study procedures
- Access to a phone capable of receiving text messages and able to participate in phone follow-ups
- Uses or willing to use a single pharmacy for prescription refills and consents to pharmacy contact
- Willing and able to provide informed consent
You will not qualify if you...
- Prescribed more than three scheduled daily medication doses
- Medication regimen includes more than five additional oral medications per dose time
- Diagnosed with secondary hypertension or blood pressure conditions not treated with standard oral antihypertensives
- Physical limitations preventing safe use of medication box or blood pressure monitor
- Living in unstable housing where medication organizer access is unsafe or inconsistent
- Moderate-to-severe cognitive impairment, dementia, or psychiatric instability preventing consent or participation
- Known allergy or contraindication to blood pressure monitor or medication box materials
- Currently participating in another trial targeting medication adherence or blood pressure control
- Planned relocation or expected unavailability during the 12-month study period
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Active, Not Recruiting
2
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
S
Sanjula Singh, MD PhD
CONTACT
E
Evy Reinders, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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