Actively Recruiting
Testing the Epley Maneuver for Treating Dizziness in the Emergency Department
Led by American University of Beirut Medical Center · Updated on 2026-05-11
118
Participants Needed
1
Research Sites
107 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this randomized controlled trial is to evaluate the efficacy of the Epley maneuver versus a sham maneuver in treating patients presenting to the emergency department (ED) with BPPV. The main questions that the study aims to answer are: * What is the mean difference in Dizziness Handicap Inventory (DHI) scores between patients receiving the Epley maneuver and those receiving the sham maneuver 3 days after enrollment? * What is the immediate response (using a 0-10-point Likert scale) of patients in each arm of the study? * What is the proportion of patients who, despite agreeing to participate, were unable to complete the full Epley maneuver due to symptom severity? Researchers will compare the Epley maneuver arm to the sham maneuver arm to see if the Epley maneuver is more effective in reducing BPPV symptoms. Participants will: * Undergo either the Epley maneuver or a sham maneuver. * Complete the Dizziness Handicap Inventory (DHI) questionnaire at baseline and 3 days post-discharge. * Patients with insufficient improvement in the sham maneuver group will receive a rescue Epley maneuver. * Have their vertigo severity assessed using a 0-10 point Likert scale at baseline, immediately and post-maneuver.
CONDITIONS
Official Title
Testing the Epley Maneuver for Treating Dizziness in the Emergency Department
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age above 18 years old
- Patients presenting to the emergency department with BPPV symptoms (single or recurrent vertigo episodes lasting up to 2 minutes)
- Positive Dix-Hallpike test showing torsional upbeating nystagmus indicating posterior semicircular canal BPPV
- Able to understand and provide signed informed consent to participate in the study
You will not qualify if you...
- Severe cervical diseases such as soft tissue disorders, cervical spondylosis, prolapsed intervertebral disks, or severe rheumatoid arthritis with cervical instability
- Unstable cardiovascular diseases including hemodynamic instability, decompensated heart failure, acute myocardial infarction, severe arrhythmias
- Suspected vertebrobasilar diseases with symptoms like cerebellar signs, vision changes, numbness, slurred speech, or confusion
- History of high-grade carotid stenosis
- Recent intake (within 24 hours) of aminoglycosides, chemotherapy agents, cyclophosphamide, loop diuretics, or quinines
- Peripheral vertigo causes other than BPPV such as Meniere's disease or vestibular neuritis
- Central vertigo causes including vestibular migraine, Arnold Chiari malformation, CNS tumors, or multiple sclerosis
- Presence of focal neurological deficits
- Vertigo episodes lasting more than 2 minutes
- Negative Dix-Hallpike test
- Pure horizontal or vertical nystagmus
- Lateral and anterior semicircular canal BPPV
- Refusal to undergo the Epley maneuver
- Pregnancy beyond 24 weeks of gestation
AI-Screening
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Trial Site Locations
Total: 1 location
1
American University of Beirut
Beirut, Lebanon
Actively Recruiting
Research Team
E
Eveline Hitti, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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