Actively Recruiting

Phase Not Applicable
Age: 19Years - 65Years
All Genders
NCT06608797

Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community

Led by Kessler Foundation · Updated on 2025-02-21

40

Participants Needed

1

Research Sites

65 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cognitive impairments are common in multiple sclerosis (MS) diagnosed both at the onset and throughout the disease course. Poor cognitive abilities have been associated with poor outcomes such as higher levels of unemployment, poor quality of life, driving difficulties among others. Learning and memory are a common cognitive deficit. This computer-based cognitive training is a 10-session treatment proven to be effective in ameliorating learning and memory in individuals with MS across 3 realms of functioning: objective cognitive performance, daily life activities and neuroimaging. Despite this strong efficacy, as well as the recent clinical application of this computer-based cognitive training across the world, recent in-person studies have highlighted that transportation to the clinic to complete treatment sessions is a significant obstacle to clinical use of this effective treatment. To address this limitation, the proposed pilot study will test the efficacy of the computer-based cognitive training administered remotely via zoom health in persons with multiple sclerosis.

CONDITIONS

Official Title

Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community

Who Can Participate

Age: 19Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • English as primary language
  • Diagnosis of multiple sclerosis
  • Between 19 and 65 years old
Not Eligible

You will not qualify if you...

  • Most recent exacerbation within one month
  • History of head injury, stroke, seizures, or other significant neurological conditions
  • Active diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder I or II
  • Poor visual acuity (corrected vision worse than 20/60 in the worse eye), diplopia, or nystagmus
  • Inability to understand and follow one, two, and three step commands
  • Intact new learning and memory (only individuals with impaired memory performance are included)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Kessler Foundation

East Hanover, New Jersey, United States, 07936

Actively Recruiting

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Research Team

S

Silvana L Costa Research Scientist, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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