Actively Recruiting
Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial
Led by VA Office of Research and Development · Updated on 2026-03-18
182
Participants Needed
1
Research Sites
173 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Obesity and post-traumatic stress disorder (PTSD) are common among Veterans. PTSD increases risk for obesity, impacting functioning, health, quality of life, and premature mortality. Use of proven treatments for PTSD and obesity in VA is low. Furthermore, Veterans with PTSD lose less weight than those without PTSD in VA's national weight management program. Based on pilot work, an integrated treatment that combines PTSD and weight management care-using behavioral and pharmacologic approaches-may improve weight and PTSD. Whether it improves these outcomes more than standard VA care is unknown, which is the focus of this study. The study also seeks to understand factors that would interfere with and facilitate implementing the program in VA if it is effective. This Veteran-centered program may be a more efficient and effective treatment for Veterans with PTSD and obesity, addressing both physical and mental health.
CONDITIONS
Official Title
Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Veteran adult
- Current PTSD Diagnosis per the revised Clinician-Administered PTSD Scale for DSM-5 (CAPS-5-R)
- Obesity: BMI of 30 kg/m2 or higher
- Enrolled in VA Puget Sound primary care to ensure safety and facilitate medication management
- Willing to participate in intervention or control groups and complete assessments
You will not qualify if you...
- Not fluent in English, severe hearing loss, or no phone access
- Recent participation in MOVE! or CPT programs (2 visits in past 2 months)
- Bariatric surgery in past 6 months or planned within next 12 months
- Use of anti-obesity medication in the past 90 days
- Current pregnancy
- History or current diagnosis of bulimia
- Unable to participate due to acute substance use, mental health, or medical exacerbation or moderate neurologic conditions such as dementia
- Current weight 600 pounds or greater
- Unable to complete standing weight and height measurements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
VA Puget Sound Health Care System Seattle Division, Seattle, WA
Seattle, Washington, United States, 98108-1532
Actively Recruiting
Research Team
M
Michelle L Upham, MSW
CONTACT
K
Katherine D Hoerster, PhD MPH BA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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