Actively Recruiting
Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease
Led by University of Pennsylvania · Updated on 2026-05-11
110
Participants Needed
2
Research Sites
160 weeks
Total Duration
On this page
Sponsors
U
University of Pennsylvania
Lead Sponsor
P
Pennsylvania Department of Health
Collaborating Sponsor
AI-Summary
What this Trial Is About
Remote healthcare monitoring for cirrhosis has shown promise in overcoming barriers to accessing specialty care, improving healthcare quality, and reducing mortality. The LiverWatch study is investigating whether a remote nutrition, physical activity, and education intervention can improve health outcomes in those with cirrhosis. In this clinical trial, individuals will be randomized to either enhanced usual care or the LiverWatch intervention. Both groups are given fitbits and asked to increase their step counts. Those in the Liverwatch group will be incentivized for increase their physical activity while also undergoing a personalized nutrition intervention and weekly symptom monitoring and cirrhosis education.
CONDITIONS
Official Title
Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- English speaking
- Aged 18 years or older
- Home-dwelling
- Diagnosis of cirrhosis with Child Turcotte-Pugh (CTP) B or C or a complication in the past 6 months such as hepatic encephalopathy, variceal bleeding, fluid overload, liver-related hospitalization, or symptom management with diuretics, non-absorbable disaccharides, rifaximin, or nonselective beta blockers
- Patient and/or caregiver is able and willing to receive SMS text messages
- Willing and able to wear personal fitness trackers and engage with study staff
You will not qualify if you...
- No access to a smartphone
- Non-home dwelling
- On hospice care
- Model for end stage liver disease (MELD) score 5
- Advanced hepatocellular carcinoma, BCLC C or higher
- Hospitalization within the last 30 days
- Deemed not appropriate by treating physician for medical reasons
- Enrolled in other dietary or physical activity interventions
- Receiving physical therapy as standard of care
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of Michigan
Ann Arbor, Michigan, United States, 48109
Not Yet Recruiting
2
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
R
Richard Mason, PharmD
CONTACT
M
Marina Serper, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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