Actively Recruiting
Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy
Led by University of Michigan · Updated on 2026-03-12
50
Participants Needed
1
Research Sites
187 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is being completed to learn if high-definition transcranial direct current stimulation (HD-tDCS) has an effect on visual and thinking abilities in persons with posterior cortical atrophy (PCA). Participants will be randomized to receive real or sham HD-tDCS (8 sessions over 4 days). Following the randomized treatment, participants will have optional open-label phase with real HD-tDCS up to 26 weeks and other possible testing.
CONDITIONS
Official Title
Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis or symptoms consistent with PCA
- Fluent in English
- Compatible with HD-tDCS
- Stable on relevant medications for at least approximately 4 weeks prior to study enrollment
- If participating in optional long-term visits remotely, a study partner is required to administer HD-tDCS; in-office participants may have a study partner but it is not required
You will not qualify if you...
- Other neurological diseases (e.g., epilepsy) or injuries (e.g., large vessel stroke, moderate-severe traumatic brain injury) that could interfere with study results
- Active relevant psychiatric conditions (e.g., bipolar disorder, schizophrenia) that may affect participation
- Recent (within 2 years) significant history or current alcohol or drug abuse/dependence
- Women who are lactating, breastfeeding, pregnant, or may be pregnant
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
Research Team
S
Stephen Schlaefflin, BS
CONTACT
E
Eileen Robinson, RN-BC
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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