Actively Recruiting

Phase Not Applicable
All Genders
Healthy Volunteers
NCT06498817

Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)

Led by Johns Hopkins Bloomberg School of Public Health · Updated on 2026-04-15

1600

Participants Needed

1

Research Sites

123 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins Bloomberg School of Public Health

Lead Sponsor

R

Research Training and Management International (RTMI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The findings from previous recent randomized controlled trials of The Cholera Hospital Based Intervention for 7 Days (CHoBI7) demonstrated that this intervention was effective in significantly reducing symptomatic cholera infections, diarrheal disease, and stunting among young children in intervention households, and had significant sustained impacts on handwashing with soap behaviors and improved water quality 12 months post intervention. Therefore, the investigators next step in the transition to scale is to: (1) To tailor the CHoBI7 program for delivery in rural health facilities and market test the CHoBI7 Program to determine the feasibility of providing a modified water, sanitation, and hygiene (WASH) package with only a soapy water bottle and chlorine tablets in both urban and rural settings through formative research and engagement of key stakeholders (Formative Research Phase); and (2) To evaluate the effectiveness of delivering the CHoBI7 program in district hospitals and sub-district health complexes in rural areas in terms of increases in WASH behaviors and decreases in diarrheal disease by conducting a randomized controlled trial (RCT) (Intervention Implementation and Evaluation Phase).

CONDITIONS

Official Title

Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diarrhea patients presenting with three or more loose stools over a 24 hour period
  • No running water inside the patient's home
  • Plan to reside in current residence for the next 3 months
  • Have a child under 5 years in the patient's household
  • Have a working mobile phone in the household
Not Eligible

You will not qualify if you...

  • No one will be excluded because of age, sex, religion, or sexual preference

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Manikganjg Sadar (District) Hospital

Mānikganj, Bangladesh, 1800

Actively Recruiting

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Research Team

C

Christine Marie George, PhD

CONTACT

T

Tahmina Parvin, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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