Actively Recruiting
Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)
Led by Johns Hopkins Bloomberg School of Public Health · Updated on 2026-04-15
1600
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
J
Johns Hopkins Bloomberg School of Public Health
Lead Sponsor
R
Research Training and Management International (RTMI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Diarrhea is a leading cause of death in children under five worldwide, and poor handwashing and water treatment habits increase the risk of diarrheal disease. This research aims to develop and test a scalable version of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7) program, which was previously shown to reduce cholera infections and improve hygiene behaviors in households. The study focuses on delivering this program in rural health facilities and evaluating its impact on water, sanitation, and hygiene (WASH) behaviors and diarrheal disease reduction through a randomized controlled trial. Participants will be assigned to one of two groups: a standard recommendation group receiving government advice on oral rehydration solution and a flyer on water treatment and handwashing, or the CHoBI7 Scale-Up Program group. The CHoBI7 group receives in-person education from health promoters on handwashing, water treatment, and safe water storage, including video testimonials and demonstrations to build homemade handwashing stations. This is reinforced by weekly voice and text messages for three months to encourage sustained behavior change. During the study, participants will be monitored over three months with assessments of handwashing frequency at key times, the number of homemade handwashing stations constructed, and water quality measures such as chlorine concentration and bacterial contamination. Researchers will also evaluate the number of diarrheal cases and psychosocial factors related to WASH behaviors. The study aims to assess the feasibility and effectiveness of delivering this modified intervention in district hospitals and health complexes to improve health outcomes in rural and urban Bangladesh.
CONDITIONS
Brief Title
Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diarrhea patients presenting with three or more loose stools over a 24-hour period
- No running water inside the patient's home
- Plan to reside in current residence for the next 3 months
- Have a child under 5 years old in the patient's household
- Have a working mobile phone in the household
You will not qualify if you...
- No one will be excluded because of age, sex, religion, or sexual preference
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 3 months
Participants receive either the standard government recommendation for oral rehydration and hygiene or the CHoBI7 Scale-Up Program involving in-person handwashing, water treatment, and safe water storage education reinforced by weekly voice and text messages for 3 months.
1 in-person visit at the health facility and weekly voice and text messages for 3 months
Duration - 3 months
Participants are monitored for handwashing behaviors, water treatment practices, and diarrheal disease outcomes during the 3 month period following intervention delivery.
Periodic assessments during the 3 months post intervention
Trial Site Locations
Total: 1 location
1
Manikganjg Sadar (District) Hospital
Mānikganj, Bangladesh, 1800
Actively Recruiting
Research Team
C
Christine Marie George, PhD
T
Tahmina Parvin, MS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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