Actively Recruiting

Age: 18Years +
All Genders
NCT06950827

Textbook Outcomes of Right Hemihepatectomy in Patients With Hepatocellular Carcinoma

Led by West China Hospital · Updated on 2025-04-30

400

Participants Needed

1

Research Sites

5 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Although traditional open right hemihepatectomy is a mature technique, the incision is usually very large; Intraoperative bleeding may be excessive, and postoperative liver failure is also prone to occur. In recent years, compared with traditional open surgery, laparoscopic surgery has many advantages, such as smaller surgical incision and faster postoperative recovery. In recent years, more and more centers have gradually transitioned to performing right hemihepatectomy through laparoscopy as much as possible. However, due to the difficulty of the surgery, steep learning curve, and postoperative complications, its adoption is limited to high-capacity surgical centers. Despite significant progress in laparoscopic liver resection technology, its clinical efficacy remains controversial, especially in laparoscopic right hemihepatectomy. More research is needed to confirm the feasibility and safety of this surgery. At present, it is unclear whether there is a difference in textbook outcomes (TO) between HCC patients undergoing open and laparoscopic right hemihepatectomy, and the association between TO and patient survival prognosis.

CONDITIONS

Official Title

Textbook Outcomes of Right Hemihepatectomy in Patients With Hepatocellular Carcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Lesion limited to the right half of the liver diagnosed as hepatocellular carcinoma by pathology and immunohistochemistry
  • Scheduled for elective right hemihepatectomy surgery
  • Preoperative liver function classified as Child Pugh A or B
  • Preoperative ASA rating of I, II, or III
Not Eligible

You will not qualify if you...

  • Confirmed cholangiocarcinoma, mixed cell carcinoma, or extrahepatic metastatic malignant tumors
  • Previous upper abdominal surgery
  • Concurrent resection of adjacent abdominal organs or major vessel and biliary reconstruction surgery except gallbladder
  • Invasion of adjacent organs (other than gallbladder), main blood vessels, bile duct cancer emboli, or distant metastases
  • Lost to follow-up or missing primary clinical data

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

West China Hospital

Chengdu, Sichuan, China, 610041

Actively Recruiting

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Research Team

J

Jiwei Huang Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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