Actively Recruiting
Textbook Outcomes of Right Hemihepatectomy in Patients With Hepatocellular Carcinoma Comparing Laparoscopic and Open Surgery
Led by West China Hospital · Updated on 2025-04-30
400
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the outcomes of right hemihepatectomy surgery in patients with hepatocellular carcinoma, a type of liver cancer. This study compares traditional open surgery with laparoscopic surgery, which uses smaller incisions and may lead to faster recovery. Despite advances in laparoscopic liver surgery, its safety and effectiveness, especially in right hemihepatectomy, remain uncertain. The study aims to determine differences in textbook outcomes and how these relate to patient survival. The study observes two groups of patients: those who underwent laparoscopic right hemihepatectomy and those who had open right hemihepatectomy. Both procedures are elective surgeries performed to remove the right half of the liver affected by cancer. Laparoscopic surgery is noted for its smaller incision and quicker recovery. Data from surgeries conducted between January 2018 and January 2023 will be analyzed to assess outcomes. Participants will have their medical records reviewed to measure textbook outcomes, overall survival, and disease-free survival over the study period. Liver function before surgery and other health ratings will be considered. The study excludes patients with certain other types of cancer, previous upper abdominal surgeries, or complex additional surgeries. Follow-up data and primary clinical information are essential for inclusion. The study is conducted by West China Hospital and runs until May 15, 2025.
CONDITIONS
Brief Title
Textbook Outcomes of Right Hemihepatectomy in Patients With Hepatocellular Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Lesion limited to the right half of the liver diagnosed as hepatocellular carcinoma by pathology
- Elective right hemihepatectomy surgery planned
- Preoperative liver function Child Pugh grade A or B
- Preoperative ASA rating of I, II, or III
You will not qualify if you...
- Pathologically confirmed cholangiocarcinoma, mixed cell carcinoma, or extrahepatic metastatic tumors
- Previous upper abdominal surgery
- Undergoing concurrent resection of adjacent abdominal organs or major vessel/bile duct reconstruction except gallbladder
- Invasion of adjacent organs except gallbladder, main blood vessels, bile duct cancer emboli, or distant metastases
- Lost to follow-up or missing primary clinical data
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to hospital discharge
Participants undergo right hemihepatectomy surgery, either laparoscopic or open, followed by immediate post-operative care.
1 hospitalization period including surgery and immediate recovery
Duration - Up to 5 years
Participants are monitored after surgery to assess recovery, overall survival, and disease-free survival.
Regular follow-up visits over several years
Trial Site Locations
Total: 1 location
1
West China Hospital
Chengdu, Sichuan, China, 610041
Actively Recruiting
Research Team
J
Jiwei Huang Professor
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here