Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
Healthy Volunteers
NCT06426498

tFUS Induced Transient Scotoma for Individual Dosing

Led by Medical University of South Carolina · Updated on 2025-08-05

30

Participants Needed

1

Research Sites

113 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purposes of this research study is to: 1. Develop a technique of transcranial Focused Ultrasound Stimulation (tFUS) where meaningful effects on the brain can be easily measured. 2. Use this technique to measure threshold for effective tFUS in individuals. 3. Determine whether disruption of conscious visual detection, versus non-conscious visually-guided behavior have different thresholds for disruption with tFUS.

CONDITIONS

Official Title

tFUS Induced Transient Scotoma for Individual Dosing

Who Can Participate

Age: 18Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female
  • Age 18-70
  • Normal or corrected-to normal vision and hearing
  • No neurological or psychological illness
Not Eligible

You will not qualify if you...

  • Diagnosis of any depressive or anxiety disorder
  • Diagnosis of schizophrenia or bipolar disorder
  • Current use of any non-prescribed psychoactive medications or drugs
  • Contraindication to enter the MRI environment
  • Pregnancy, suspected pregnancy, or plan to become pregnant soon
  • Inability to follow the treatment schedule
  • Starting new antidepressant treatment at study start
  • Non-English speaking
  • Children, prisoners, and institutionalized individuals will not be recruited

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Medical University of South Carolina Brain Stimulation Division

Charleston, South Carolina, United States, 29425

Actively Recruiting

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Research Team

B

Bridgette Holland

CONTACT

M

Mark S George, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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tFUS Induced Transient Scotoma for Individual Dosing | DecenTrialz