Actively Recruiting
The Therapeutic Effect of Betaine in Syringomyelia
Led by Xuanwu Hospital, Beijing · Updated on 2024-03-13
30
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Purpose: This clinical trial aims to evaluate the indications, therapeutic effects and side effects of betaine in refractory syringomyelia. Primary outcome measure: The primary endpoint is the change of ASIA at week 12. The clinical efficacy is defined as ASIA increase ≥ 1 at week 12, as compared with that before betaine usage.
CONDITIONS
Official Title
The Therapeutic Effect of Betaine in Syringomyelia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Contraindication to duraplasty and shunting treatment due to history or high risk of severe adverse effects
- No effective response to duraplasty and shunting treatment in the 12 months before study entry
- Estimated life expectancy greater than 12 months
- Ability to understand and willingness to sign informed consent, or a caregiver who can do so
- Ability to swallow tablets
You will not qualify if you...
- Cardiometabolic disease requiring prescribed medications
- Evidence of tumor metastasis, recurrence, or invasion
- History of psychiatric diseases
- History of seizures
- History of arteriosclerotic cardiovascular diseases within 6 months
- New York Heart Association Grade II or greater congestive heart failure
- Serious and uncontrolled cardiac arrhythmia
- Significant vascular disease such as moderate or severe carotid stenosis, aortic aneurysm, or aortic dissection
- Severe infection
- History of allergy to relevant drugs
- Pregnancy, lactation, or fertility program in the next 12 months
- History or current diagnosis of peripheral nerve disease
- Abnormal liver or renal function
- Active tuberculosis
- Transplanted organs
- Human immunodeficiency virus
- Participation in other experimental studies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fengzeng Jian
Beijing, Beijing Municipality, China, 100053
Actively Recruiting
Research Team
J
jian fengzeng
CONTACT
C
chenghua yuan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here