Actively Recruiting

Phase 2
Phase 3
Age: 60Years - 75Years
All Genders
NCT02836158

Therapeutic Effects of R-IDARAM and Intrathecal Immunochemotherapy on Elderly Patients With PCNSL

Led by Navy General Hospital, Beijing · Updated on 2020-09-09

100

Participants Needed

1

Research Sites

1056 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study suggests that R-IDARAM combined with intrathecal immunochemotherapy may be high effective in elderly patients with primary central nervous system lymphoma (PCNSL).

CONDITIONS

Official Title

Therapeutic Effects of R-IDARAM and Intrathecal Immunochemotherapy on Elderly Patients With PCNSL

Who Can Participate

Age: 60Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Newly diagnosed histologically proven non-Hodgkin's lymphoma (NHL).
Not Eligible

You will not qualify if you...

  • Lymphoma involvement outside the brain, meninges, cerebrospinal fluid, or eyes.
  • Age less than 18 years or greater than 75 years.
  • Low bone marrow function with neutrophils below 1.5 x 10^9/L, platelets below 100 x 10^9/L, or hemoglobin less than 8 g/dL.
  • Known immunosuppression such as HIV type I infection.
  • History of any previous cancer.
  • Kidney function with creatinine clearance below 60 mL/min.
  • Heart failure classified as NYHA IIIB or IV.
  • Uncontrolled infections.
  • Active lung or liver disease that is not compensated.
  • Prior treatment for primary central nervous system lymphoma except corticosteroids.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Navy General Hospital

Beijing, Beijing Municipality, China, 100048

Actively Recruiting

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Research Team

L

Liren Qian, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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