Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07362719

Therapeutic Efficacy of the Phlebology-oriented Thermal Cure at the Saint-Eloy Thermal Center in the Treatment of Symptoms of Severe Chronic Venous Insufficiency

Led by Société d'Exploitation des Thermes d'Amnéville · Updated on 2026-03-02

84

Participants Needed

1

Research Sites

61 weeks

Total Duration

On this page

Sponsors

S

Société d'Exploitation des Thermes d'Amnéville

Lead Sponsor

S

Slb Pharma

Collaborating Sponsor

AI-Summary

What this Trial Is About

Chronic venous insufficiency (CVI) is a common progressive vascular disease that affects nearly one-third of the French population. Despite considerable advances in the treatment of chronic venous insufficiency, this condition remains a burden for patients and national healthcare systems. Balneotherapy-which includes thermal cures-is part of the therapeutic arsenal used in the treatment of chronic venous insufficiency. It is a relatively effective alternative with a relatively low cost compared to drug or surgical treatments. Phlebology is a thermal treatment orientation recognized by the French social security system. The Saint-Eloy Thermal Center is listed among the thermal stations approved by the French Ministry of Health. It currently uses thermal water from Amnéville-les-Thermes to treat rheumatological and respiratory conditions, and wants to expand its range of orientations by adding phlebology. The AMNEVILLE-PHL study therefore aims to evaluate the efficacy and safety of the Saint-Eloy thermal cure for phlebology in patients suffering from severe chronic venous insufficiency.

CONDITIONS

Official Title

Therapeutic Efficacy of the Phlebology-oriented Thermal Cure at the Saint-Eloy Thermal Center in the Treatment of Symptoms of Severe Chronic Venous Insufficiency

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • Severe chronic venous insufficiency of the lower limbs (C4a,b,c - C5) confirmed by venous Doppler ultrasound
  • Indicated for a thermal cure focused on phlebology
  • Available for a 3-week consecutive thermal cure at Saint-Eloy Thermal Center and 6 months follow-up
  • Able to attend scheduled visits and complete data collection
  • Women of childbearing age using effective contraception
  • Affiliated with a health insurance plan or beneficiary
  • Provided written informed consent for participation
Not Eligible

You will not qualify if you...

  • Contraindication to thermal cure
  • Participation in any thermal cure within the last 9 months
  • Healed lower limb ulcer within the last 3 months
  • No venous trophic disorders or only mild chronic venous insufficiency (class C3 or less) in both legs
  • Open ulcer on lower limb (class C6)
  • Planned interventional venous treatment within next 6 months
  • Scheduled orthopedic surgery on lower limbs within next 6 months
  • Unable to walk
  • Known allergy to sulfur
  • Significant medical conditions affecting safety or study participation
  • Participating in another clinical trial or exclusion period not ended
  • Vulnerable persons as defined by French Public Health Code

AI-Screening

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Trial Site Locations

Total: 1 location

1

Centre Thermal Saint-Eloy

Amnéville, France, 57360

Actively Recruiting

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Research Team

Y

Youna PERON

CONTACT

G

Guillaume DUMAS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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