Actively Recruiting
The Therapy of Large Endometrioma
Led by University Hospital, Lille · Updated on 2025-12-23
62
Participants Needed
1
Research Sites
305 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Endometrioma's prevalence is between 23 and 55%. It causes pelvic pain, decrease fertility and ovarian reserve. Currently, there's no recommendation about large endometrioma's treatment and there's no information on the best treatment to limit recurrences, preserve fertility and ovarian reserve. In Lille university hospital, simple laparoscopic drainage associated with hormonal therapy is practiced to reduce the risk of cystectomy. This protocol will be evaluated with an observational and prospective study, including women of childbearing age having endometrioma measuring 6 cm or above. The aim of this study is to assess if cyst drainage associated with GnRH agonist, could decrease endometrioma recurrences, deleterious effect on ovarian reserve and evaluate impact on anti-mullerian hormone
CONDITIONS
Official Title
The Therapy of Large Endometrioma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Endometrioma size 6 cm confirmed by MRI or ultrasonography
- Women with isolated endometrioma or with other extraovarian endometriosis such as peritoneal, infiltrating lesions, and adenomyosis
- Single or bilateral cysts
- Female participants aged between 18 and 40 years
You will not qualify if you...
- Cysts showing atypical features on imaging or laparoscopy
- Pregnancy
- Contraindication to GnRH agonist therapy (Enantone� 3.75 mg or Decapeptyl� 3 mg)
- Contraindication to laparoscopy
- Contraindication to general anesthesia
- Refusal to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hop Jeanne de Flandre Chu Lille
Lisle-sur-Tarn, France, 59037
Actively Recruiting
Research Team
C
Chrytèle RUBOD, MD,PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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