Actively Recruiting
Theravex Oral and Theravex Tissue Care Plus in the Healing Process of Mucogingival Surgery
Led by Universidad Complutense de Madrid · Updated on 2026-02-24
30
Participants Needed
1
Research Sites
72 weeks
Total Duration
On this page
Sponsors
U
Universidad Complutense de Madrid
Lead Sponsor
B
Biointelligent Technology Systems SL
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical study assesses the efficacy of two novel bioactive solutions, Theravex Oral and Theravex Tissue Care Plus, in enhancing soft tissue healing after periodontal surgery. The study focuses on patients undergoing a Modified Free Gingival Graft (M-FGG) technique to treat gingival recessions around mandibular incisors. Participants are randomly assigned to a test group receiving the Theravex treatment or a control group receiving a saline placebo. The primary goal is to measure the impact of these solutions on root coverage and other key outcomes, such as tissue gain, color integration, and postoperative pain, over a one-year period.
CONDITIONS
Official Title
Theravex Oral and Theravex Tissue Care Plus in the Healing Process of Mucogingival Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy patients aged 18 years or older
- At least one mandibular incisor with gingival recession RT1 or RT2 requiring a free gingival graft
- Periodontal health with plaque index 20% or less
- Initial probing depth 3 mm or less on treated teeth
- No dental mobility greater than grade 1 on treated teeth
- Well-defined cementoenamel junction (CEJ)
- Signed informed consent to participate in the study
You will not qualify if you...
- Smoking 10 or more cigarettes per day
- Previous treatment with Theravex products
- Untreated parafunctional habits
- Restorations that cannot be removed for proper treatment
- Pregnancy or uncertain pregnancy status
- Uncontrolled systemic diseases, neurological or psychiatric disorders, or other conditions affecting study results
- Not attending follow-ups or lack of signed informed consent
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Complutense University of Madrid
Madrid, Madrid, Spain, 28040
Actively Recruiting
Research Team
M
Mariano Sanz Alonso, DMD, MD, PHD
CONTACT
A
Andrea Dobos, DMD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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