Comparison of the Effects of Different Surgical Techniques on the Degree of Thermal Artifact in Patients Undergoing Conization A Clinical Study

What this Trial Is About

This research evaluates different surgical techniques used in conization to treat cervical intraepithelial neoplasia, focusing on how these methods affect the presence of thermal artifacts in tissue samples. These thermal artifacts can make it harder for doctors to examine tissue under a microscope and assess surgical margins properly. The study compares three variations of electrosurgical conization used in a hybrid technique combining electrosurgery and cold knife conization. Participants will undergo one of three procedures conization with electrosurgery set at 50 watts pure cut, conization with electrosurgery set at 50 watts blend mode, or a hybrid method using both 50 watts pure cut electrosurgery and a cold knife. These methods are evaluated to determine which causes fewer thermal artifacts and allows better tissue evaluation. During the study, researchers will assess the degree of thermal artifact within seven days after surgery and evaluate the cervical transformation zone four months post-operation. Participants will be monitored through these follow-up periods to help understand the impact of each surgical technique on tissue quality and margin assessment, with the total involvement lasting at least four months after the procedure.

Thermal Artifact in Patients Undergoing Conization: A Clinical Study