Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT07321925

Thermoacoustic Method for Estimating Liver Fat Fraction

Led by Endra Lifesciences · Updated on 2026-01-07

49

Participants Needed

1

Research Sites

19 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to use our Thermoacoustic Enhanced Ultrasound device to measure the fat levels in your liver and compare it to the the gold standard MRI PDFF measurements. Participants will have a scan with our device, then they will go have an abdominal MRI completed. The goal is to create a more accessible device to measure liver fat as it is an indicator for overall health and metabolic diseases.

CONDITIONS

Official Title

Thermoacoustic Method for Estimating Liver Fat Fraction

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Study participants are 18 or older.
  • Able to understand, read, and provide written informed consent in English.
  • Able to tolerate both ultrasound and MRI examinations.
  • Able to lie flat, or on their side, for 20 minutes and pause breathing for up to 10 seconds.
Not Eligible

You will not qualify if you...

  • Metal or electronic implants, including pacemakers, metal clips, drug delivery pumps, hip implants, and neural stimulation devices, contraindicated for MRI.
  • Known pregnancy on the day of consent or becoming pregnant during study participation.
  • Liver diseases other than MASLD/MASH/fibrosis, including cirrhosis, hepatocellular carcinoma, and ascites.
  • Broken or injured skin in the right upper abdominal quadrant.
  • Body habitus or anatomical variation preventing liver access with ultrasound through the right intercostal imaging window.
  • BMI greater than 50 kg/m2.
  • Subcutaneous fat at measurement location less than or equal to 6mm.
  • Missing liver lobe.
  • Peri-hepatic fat at the measurement location.
  • Focal liver lesions or anatomical structures in the measurement location as detected by ultrasound.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

ENDRA Life Sciences

Ann Arbor, Michigan, United States, 48105

Actively Recruiting

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Research Team

Z

Ziad Rouag

CONTACT

A

Ava Ohlgren

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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