Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05351242

Thermotherapy Against Persistent Bacterial LUNG Infections

Led by Chronic Obstructive Pulmonary Disease Trial Network, Denmark · Updated on 2023-08-31

150

Participants Needed

1

Research Sites

187 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to determine whether an intervention with frequent thermotherapy will be able to reduce the amount of colonizing bacteria in the bronchoalveolar lavage sample and eradicate the colonizing bacteria.

CONDITIONS

Official Title

Thermotherapy Against Persistent Bacterial LUNG Infections

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Competent and capable of participating in the study
  • Lung function (FEV1) greater than 1.0 liter
  • At least two positive sputum or bronchoalveolar lavage cultures in the last 24 months for one of these bacteria: Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Staphylococcus aureus, Haemophilus influenzae, Achromobacter xylosoxidans, Klebsiella oxytoca, or Klebsiella pneumoniae
  • At least one positive bacterial culture after antibiotic treatment
  • Willing to either attend sauna sessions at a minimum temperature of 85°C for at least 7 minutes, four times weekly for six months, or avoid sauna use for six months
Not Eligible

You will not qualify if you...

  • Allergy to lidocaine or midazolam
  • Contraindications to bronchoscopy
  • History of severe laryngospasm requiring intubation
  • Pregnancy or breastfeeding
  • Severe language difficulties or inability to provide informed consent
  • Severe uncontrolled mental illness (patients with controlled mental illness may participate)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Herlev and Gentofte University hospital

Hellerup, Capital Region, Denmark, 2900

Actively Recruiting

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Research Team

M

Mohamad I Saeed, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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