Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT06566521

Thoracic Paravertebral Block in Daytime Laparoscopic Partial Adrenalectomy

Led by Shanxi Bethune Hospital · Updated on 2024-10-31

80

Participants Needed

1

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Day surgery refers to the entire diagnostic and therapeutic process completed within 24-48 h, including patient admission, surgery, and discharge. Research by Shariq et al suggested that daytime laparoscopic adrenalectomy was a safe and effective alternative to traditional inpatient treatment. Li et al demonstrated that daytime surgery for laparoscopic partial adrenalectomy could reduce hospital stays, lower medical costs, and optimize healthcare resource utilization. The day surgery has put forward higher requirements for the management of perioperative anesthesia, in which the postoperative multimodal analgesia is particularly important.Thoracic paravertebral block (TPVB) is a regional block technique in which local anaesthetics can be injected into paravertebral space to block the ipsilateral sympathetic and somatosensory nerves. TPVB single point injection can achieve sensory block of 3-6 spinal ganglia on one side, with minimal impact on respiratory, gastrointestinal and bladder function. Especially, TPVB does not affect motor nerve, which enable patients to perform painless functional exercise shortly after surgery, promote rapid recovery, and enhance satisfaction and comfort. A large number of previous studies have shown that TPVB had become increasingly popular for postoperative analgesia after thoracic or breast surgery. However, to our knowledge, few studies to date have investigated the application of TPVB in daytime adrenal surgery. Therefore, we conducted this randomized clinical trial to examine the effect of TPVB on postoperative analgesia and the quality of recovery in patients following daytime laparoscopic partial adrenalectomy.

CONDITIONS

Official Title

Thoracic Paravertebral Block in Daytime Laparoscopic Partial Adrenalectomy

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 to 70 years
  • Body Mass Index (BMI) 18.5 to 30 kg/m²
  • American Society of Anesthesiologists (ASA) grade I to II classification
  • Unilateral non-functional adrenal adenoma with tumor diameter greater than 20 mm
Not Eligible

You will not qualify if you...

  • Peripheral nervous system disease
  • Spinal deformity or surgery
  • Puncture site infection or coagulation abnormalities
  • History of postoperative nausea and vomiting or allergy to local anesthetics
  • Unstable mental illness or refusal to participate

AI-Screening

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Trial Site Locations

Total: 1 location

1

Shanxi Bethune Hospital

Taiyuan, Shanxi, China, 030032

Actively Recruiting

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Research Team

J

Jian-Wen Zhang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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