Actively Recruiting
A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism
Led by Hoopes Vision · Updated on 2025-10-01
120
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This purpose of this study is to compare a new form of LASIK called Ray Tracing Guided LASIK to 3 other forms of corneal refractive surgery: 1. KLEx (KeratoLenticule Extraction) using the Zeiss Visumax 800 Laser, 2. WFO LASIK (Wavefront Optimized LASIK) using the Alcon EX500 Laser, and 3. Topography Guided LASIK (Contoura LASIK) also using the Alcon EX500 Laser.
CONDITIONS
Official Title
A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 22 to 50 years at the time of consent
- Diagnosis of myopia or myopia with astigmatism with preoperative spherical equivalent refraction between -2.00 and -9.00 diopters
- Preoperative spherical component between -2.00 and -8.00 diopters
- Refractive cylinder of 0.00 to -3.00 diopters
- Best corrected visual acuity of 20/20 or better in each eye
- Stable refraction with no more than 0.50 diopter change in spherical equivalent over 12 months or more
- Contact lens wearers must stop soft lenses at least 5 days and hard or gas-permeable lenses at least 4 weeks before preoperative screening; soft lens wearers may resume after testing but must stop again 5 days before surgery
- Acceptable preoperative tomography and examination results for refractive surgery as determined by the Principal Investigator
- Surgical plan targets emmetropia in both eyes with no monovision
- Willing and able to use postoperative medications as prescribed
- Able to complete all preoperative and postoperative questionnaires, tests, and exams
- Willing and able to return for all postoperative visits
You will not qualify if you...
- Clinically significant dry eye on examination
- Irregular astigmatism, keratoconus, keratoconus suspect, or abnormal corneal tomography
- History of corneal dystrophies or guttata
- History of herpetic keratitis or active disease
- Previous refractive surgery
- History of glaucoma or glaucoma suspect
- Uncontrolled diabetes, unstable hypertension, or unstable autoimmune disease
- Females who are pregnant, breastfeeding, or plan to become pregnant during the study
- Determined by the Principal Investigator as not a good candidate for the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hoopes Moshirfar Research Center
Draper, Utah, United States, 84020
Actively Recruiting
Research Team
S
Steven H Linn, OD
CONTACT
S
Shealynn Petersen, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
6
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