Actively Recruiting
Thrombotic Microangiopathy (TMA) Associated With Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) In Adult Patients
Led by ITAC (Instituto de Trasplantes y Alta Complejidad) · Updated on 2025-07-14
200
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Thrombotic Microangiopathy (TMA) Associated with Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) is a serious complication that is associated with increased morbidity, related to multiple organ failure, with increased mortality in transplant patients. The incidence and evolution of TMA, especially in the adult population, is unclear due to the lack of early systematic screening and clear criteria for its diagnosis. For this reason, we designed this protocol to study the incidence and evolution of TMA Associated with allogeneic HSCT in adult patients from Argentina.
CONDITIONS
Official Title
Thrombotic Microangiopathy (TMA) Associated With Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) In Adult Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (18 years or older) undergoing allogeneic HSCT in specialized centers with routine clinical/laboratory screening for TMA
- Patients with three or more laboratory or clinical markers of TMA in two consecutive assessments within 14 days, including: elevated schistocytes in blood, LDH above normal, new thrombocytopenia or need for platelet transfusion, new anemia or need for red blood cell transfusion, high blood pressure (≥140/90), or proteinuria
- Patients suspected or diagnosed with TMA who have signed specific study consent
You will not qualify if you...
- Participation in any interventional treatment study for TMA
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Instituto de Trasplantes de Alta Complejidad (ITAC)
Buenos Aires, Argentina, C1425EGH
Actively Recruiting
Research Team
M
Maria Belen Rosales Ostriz, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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