Actively Recruiting
Thromboxane Function in Women With Endometriosis
Led by Penn State University · Updated on 2025-05-04
96
Participants Needed
1
Research Sites
186 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: * Do women with endometriosis have greater blood pressure and pain responses to a stimulus than healthy women? * Do women with endometriosis have greater platelet activity than healthy women? Participants will take aspirin and/or placebo and will: * perform hand grip exercise and cold pressor tests * undergo iontophoresis and blood draw Researchers will compare women with and without endometriosis to see if there is a difference in neurovascular regulation.
CONDITIONS
Official Title
Thromboxane Function in Women With Endometriosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Born with a uterus
- 18-45 years old
- Women with and without endometriosis
You will not qualify if you...
- Currently pregnant or breastfeeding
- Diagnosed cardiovascular disease
- Body mass index over 35
- Use of nicotine products such as smoking, chewing tobacco, or vaping
- Current or recent (within 6 months) hormone replacement therapy
- Known skin allergies, current rash, skin disease, or pigmentation disorders
- Diabetes
- Kidney disease, renal artery stenosis, or kidney impairment
- Liver disease
- Stage II hypertension (blood pressure over 140/90 mmHg)
- Low blood pressure (below 90/60 mmHg)
- Raynaud's syndrome
- Use of medications that could affect cardiovascular responses (e.g., antihypertensives, diuretics, digoxin)
- Allergy or sensitivity to investigational agents
- Immunosuppressed or immunocompromised status
AI-Screening
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Trial Site Locations
Total: 1 location
1
Noll Laboratory
University Park, Pennsylvania, United States, 16802
Actively Recruiting
Research Team
L
Lacy Alexander, Ph.D.
CONTACT
S
Sue Slimak, RN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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