Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07079657

Thulium Laser and Growth Factors for Androgenetic Alopecia - a Prospective, Clinical Study

Led by Universitätsklinikum Hamburg-Eppendorf · Updated on 2025-07-23

30

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Androgenetic alopecia (AGA) is a common cause of hair loss affecting up to 70% of men and 40% of women, mainly on the frontal and parietal scalp. This condition can cause significant emotional and psychological distress. Researchers are studying different therapies for AGA, including topical treatments, platelet-rich plasma, hair transplantation, and laser therapies like the thulium laser combined with growth factors. Despite its growing use, there are few studies assessing the benefits of thulium laser with growth factors and LED phototherapy. This study compares three treatment approaches: thulium laser alone, thulium laser combined with growth factor serum, and thulium laser with growth factor serum plus LED phototherapy. Each intervention consists of three sessions spaced six weeks apart. Participants will be randomly assigned to one of these three groups to evaluate the effects of these therapies on hair loss. Participants will attend sessions at baseline and follow-up visits at 1 and 6 months post-treatment. During these visits, researchers will measure hair density, hair thickness, and overall aesthetic improvement using a global scale. Pain levels during the procedures will also be recorded. The study aims to provide objective and patient-reported data on these laser therapies over a 6-month period.

CONDITIONS

Brief Title

Thulium Laser and Growth Factors for Androgenetic Alopecia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women aged 18 and over
  • Good general health with no relevant previous illnesses
  • Presence of androgenetic alopecia (AGA)
  • Ability and willingness to provide informed consent
  • Willing and able to attend follow-up visits
Not Eligible

You will not qualify if you...

  • Younger than 18 years
  • Pregnant or breastfeeding women
  • Scarring alopecia or alopecia due to skin diseases or chemical/physical damage
  • Significant scarring or open wounds in the treatment area
  • Metallic implants in the head region
  • Mental illnesses such as psychoses or body perception disorders
  • Use of isotretinoin, retinoids, psychotropic drugs, coumarins, or heparins within the last 2 weeks
  • Resurfacing treatments in the affected area within 2 months before or during the study
  • Tendency to excessive scarring
  • Lack of informed consent or data protection agreement

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Approximately 12 weeks

Participants receive one of three treatments involving Thulium laser with or without growth factor serum and LED in 3 sessions at intervals of 6 weeks.

3 treatment sessions at 6-week intervals

Follow-up

Duration - Up to 6 months post-treatment

Participants are assessed for treatment effects including aesthetic improvement, hair density, and hair thickness.

Visits at 1 month and 6 months post-treatment

Trial Site Locations

Total: 1 location

1

University Medical Center Hamburg-Eppendorf

Hamburg, Free and Hanseatic City of Hamburg, Germany, 20246

Actively Recruiting

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Research Team

L

Lynhda Nguyen, Dr. med.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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