Actively Recruiting
THUMB: Multi-centre Cluster Trial for Caesarean Section Haemorrhage
Led by Bruce Biccard · Updated on 2026-04-13
2400
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The quality improvement project evaluating the delivery of a perioperative care complex intervention to improve haemorrhage-related outcomes in patients undergoing caesarean section. The objectives of the current study will be: 1. To evaluate whether implementation of the 'Rule of THUMB' perioperative complex intervention increases risk assessment, diagnosis and compliance with proven interventions for haemorrhage during and after caesarean section. 2. To understand the influence of contextual and socio-dynamic factors on how the trial results were achieved and how the intervention mechanisms did, or did not, work in practice (the process evaluation). The findings from this study will be used subsequently to modify and improve the quality improvement intervention, so that it can be delivered at scale across Africa and assess its impact on haemorrhage during and after caesarean section in the future.
CONDITIONS
Official Title
THUMB: Multi-centre Cluster Trial for Caesarean Section Haemorrhage
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Any patient who requires a caesarean section in participating countries with hospitals that routinely perform caesarean section.
You will not qualify if you...
- Patients who opt out of the trial will be excluded.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mowbray Maternity Hospital
Cape Town, South Africa
Actively Recruiting
Research Team
M
MARGOT FLINT, PhD
CONTACT
B
BRUCE BICCARD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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