Actively Recruiting

Age: 18Years +
All Genders
NCT06963203

Thyroidectomy for Graves' Disease or Amiodarone-induced Thyrotoxicosis

Led by Andrea Goldmann · Updated on 2025-07-02

486

Participants Needed

15

Research Sites

126 weeks

Total Duration

On this page

Sponsors

A

Andrea Goldmann

Lead Sponsor

S

Spital Männedorf

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to learn about the potential differences in morbidity of thyroidectomy (removal of the thyroid gland) depending on the preoperative hormonal status. The main question it aims to answer is: Do patients undergoing thyroidectomy for thyreotoxicosis (thyroid hyperfunction) due to Graves' disease or Amiodarone induced thyreotoxicosis have comparable complication rates depending on their thyroid metabolic status prior or during the procedure. The data from participants undergoing a thyroidectomy at one of the study sites will be prospectively registered in the EUROCRINE registry, including an add-on module for additional study specific routine data. The operation itself, the preoperative or postoperative treatments are not altered in any way.

CONDITIONS

Official Title

Thyroidectomy for Graves' Disease or Amiodarone-induced Thyrotoxicosis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients 18 years or older undergoing thyroid surgery for Graves' disease or Amiodarone-induced thyrotoxicosis with confirmed hyperthyroidism or on specific medication for these conditions
  • Patients who have signed informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Children and minors under 18 years of age
  • Pregnant women
  • Patients unable or unwilling to give informed consent due to language or intellectual difficulties
  • Patients having additional parathyroid surgery, lymph node removal, or repeat thyroid surgery
  • Patients undergoing thyroid surgery for reasons other than Graves' disease or Amiodarone-induced thyrotoxicosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 15 locations

1

OLV Ziekenhuis

Aalst, Belgium

Actively Recruiting

2

Universite de Lorraine, Cru Nancy

Nancy, France

Actively Recruiting

3

Evgenidion Hospital Athens

Athens, Greece

Actively Recruiting

4

Universitario Virgen de las Nieves

Granada, Spain

Actively Recruiting

5

Hospital Costa del Sol

Marbella, Spain

Actively Recruiting

6

Kantonsspital Winterthur

Zurich, Winterthur, Switzerland, 8400

Actively Recruiting

7

Clarunis St. Clara Spital

Basel, Switzerland

Not Yet Recruiting

8

Universitätsspital Bern, Inselspital

Bern, Switzerland

Actively Recruiting

9

University Hospitals of Geneva

Geneva, Switzerland

Actively Recruiting

10

University Hospital of Lausanne CHUV

Lausanne, Switzerland

Actively Recruiting

11

Kantonsspital Basel Land

Liestal, Switzerland

Not Yet Recruiting

12

Spital Männedorf

Männedorf, Switzerland

Actively Recruiting

13

Ospedale Regionale di Mendrisio

Mendrisio, Switzerland

Actively Recruiting

14

HOCH Kantonsspital St. Gallen

Sankt Gallen, Switzerland

Actively Recruiting

15

Spital Limmattal

Schlieren, Switzerland

Actively Recruiting

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Research Team

A

Andrea Goldmann, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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