Actively Recruiting

Phase 3
Age: 18Years - 75Years
All Genders
NCT06196047

Ticagrelor Versus Cilostazol in Minor Ischemic Stroke or TIA

Led by Kafrelsheikh University · Updated on 2024-08-20

900

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Along with the current clinical trial, the efficacy and safety of ticagrelor and aspirin administered within the first 24 hours of first-ever ischemic stroke compared to cilostazol and aspirin were assessed through NIHSS, mRS, and possible adverse effects.

CONDITIONS

Official Title

Ticagrelor Versus Cilostazol in Minor Ischemic Stroke or TIA

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 75 years
  • First-ever acute minor ischemic stroke or transient ischemic attack (TIA)
  • Received antiplatelet treatment within 24 hours of stroke onset
  • Not eligible for rt-PA treatment
Not Eligible

You will not qualify if you...

  • Not followed up for 90 days after enrollment
  • NIHSS score greater than 4
  • History of persistent or recurrent central nervous system diseases like epilepsy, meningioma, multiple sclerosis, or residual neurological deficits from head trauma
  • Clinical seizures at stroke onset
  • Symptoms of major organ failure or active cancer
  • Acute myocardial infarction within the previous six weeks
  • Use of warfarin, regular ticagrelor within the week before admission, or chemotherapy in the last year
  • Active peptic ulcers, gastrointestinal surgery, or bleeding history within the last year
  • Major surgery within the last three months
  • Known allergy to study drugs
  • INR > 1.4 or PT > 18
  • Blood glucose less than 50 or greater than 400 mg/dL
  • Blood pressure less than 90/60 or greater than 185/110 mmHg on admission
  • Platelet count less than 100,000
  • Pregnant or lactating
  • Stroke due to venous thrombosis, wake-up stroke, or stroke following cardiac arrest or severe low blood pressure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Kafr Elsheikh University Hospital

Kafr ash Shaykh, Egypt, 33155

Actively Recruiting

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Research Team

M

mohamed G Zeinhom, MD

CONTACT

S

sherihan R. ahmed, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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