Actively Recruiting
Ticino Artificial InTelligence integrAtioN for Occlusion Myocardial Infarction
Led by Cardiocentro Ticino · Updated on 2026-05-05
500
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate whether an artificial intelligence (AI)-based ECG interpretation tool improves the early diagnosis and treatment of occlusion myocardial infarction (OMI) in adults presenting with suspected acute coronary syndrome (ACS) who do not meet traditional ST-elevation myocardial infarction (STEMI) criteria. The main questions it aims to answer are: 1. Does AI-assisted ECG interpretation enable more timely identification and treatment of OMI, as defined by earlier initiation of coronary intervention? 2. Does AI-assisted diagnosis reduce infarct size, measured by peak high-sensitivity troponin T (hsTnT) levels? Researchers will compare AI-assisted ECG interpretation to standard care to determine if the AI tool improves clinical outcomes and care timelines. Participants will: 1. Present with symptoms suggestive of ACS but without clear STEMI criteria 2. Be randomized 1:1 to either AI-assisted or standard ECG interpretation 3. Undergo follow-up assessments for cardiovascular outcomes, including 30-day death, time to treatment of total coronary occlusion, and peak hsTnT levels
CONDITIONS
Official Title
Ticino Artificial InTelligence integrAtioN for Occlusion Myocardial Infarction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Presenting with symptoms suspected of ongoing acute myocardial ischemia such as chest pain, shortness of breath, sweating, nausea or vomiting, pain radiating to shoulder, arm, jaw, or back, fatigue, or light-headedness
- Able to provide informed consent
You will not qualify if you...
- Clear diagnosis of ST-segment elevation myocardial infarction (STEMI) by managing physicians
- Pregnancy or lactation
- Unable to provide informed consent due to legal incompetence
- Symptoms started more than 24 hours before clinical presentation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cardiocentro Ticino Institute
Lugano, Canton Ticino, Switzerland, 6900
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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