Actively Recruiting

Age: 18Years +
All Genders
NCT06922162

Tickle Stimulation in Disorders of Consciousness (DoC)

Led by Anna Estraneo · Updated on 2025-04-23

45

Participants Needed

2

Research Sites

122 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this project is to investigate whether tickling stimulations can have a short-term effect on the responsiveness of patients with Disorders of Consciousness due to Severe Acquired Brain Injury and to compare this effect with that of neutral tactile stimulations that do not induce tickling.

CONDITIONS

Official Title

Tickle Stimulation in Disorders of Consciousness (DoC)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of disorders of consciousness (DoC) based on the CRS-R scale
  • Age 18 years or older
  • Time since the event 28 days or more
Not Eligible

You will not qualify if you...

  • Large craniectomy that may interfere with fNIRS recording
  • Unstable clinical conditions such as respiratory failure, fever, or status epilepticus
  • Fractures, paralysis, injuries, or muscular dystrophy preventing proper stimulation of body parts
  • Lack of informed consent from the legal representative

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Coma Science Group - University of Liege

Liège, Belgium, Belgium, 4000

Completed

2

Fondazione Don Gnocchi

Sant'Angelo dei Lombardi, Avellino, Italy, 83054

Actively Recruiting

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Research Team

S

Simona Abagnale, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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