Actively Recruiting
Time to Ambulation After ProGlide Closure
Led by Chinese Academy of Medical Sciences, Fuwai Hospital · Updated on 2026-01-23
300
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Transradial access has become the standard for coronary procedures due to fewer vascular complications and shorter bed rest, yet transfemoral access remains essential for complex peripheral interventions requiring larger sheaths and stronger support. Vascular closure devices (VCDs), particularly suture-mediated devices such as ProGlide, have improved femoral access by reducing hemostasis time, ambulation delay, and patient discomfort. Although early ambulation after ProGlide closure has been reported, current practice varies widely, and the relationship between ambulation timing and vascular complications remains unclear. This trial aims to evaluate the effect of different ambulation times after ProGlide closure in transfemoral peripheral angiography or intervention, with the goal of identifying the optimal time to ambulation that balances safety and efficiency.
CONDITIONS
Official Title
Time to Ambulation After ProGlide Closure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled for peripheral angiography or endovascular intervention via transfemoral access
- Femoral artery puncture site located at the common femoral artery
- Use of 6-8F vascular sheath
- Hemostasis achieved with 6F ProGlide closure device, with no active bleeding, hematoma, or limb ischemia after closure
- Preoperative ankle-brachial index (ABI) greater than 0.9 on both sides
- Conscious, cooperative, and with normal lower limb mobility
You will not qualify if you...
- Undergoing carotid artery intervention
- Femoral artery diameter less than 5 mm or effective lumen less than 5 mm due to plaque
- History of vascular complications at the puncture site
- Abnormal heart or lung function
- Platelet count less than 80 x 10⁹/L during procedure or use of thrombolytic agents
- Cognitive impairment, uncooperative, or limited lower limb mobility
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, Beijing Municipality, China, 100037
Actively Recruiting
Research Team
H
Hui Dong, MD
CONTACT
X
Xiongjing Jiang, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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