Actively Recruiting

Age: 18Years +
All Genders
NCT07433634

Time to BBVNA Relief

Led by Yale University · Updated on 2026-03-03

200

Participants Needed

3

Research Sites

127 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Basivertebral nerve ablation (BVNA) is a minimally invasive procedure approved for vertebrogenic low back pain. While early studies support its efficacy, real-world evidence is still evolving, particularly regarding the trajectory of pain relief and functional improvement over time, and predictors of clinical response. This study aims to evaluate clinical outcomes longitudinally following BVNA and identify baseline predictors of response.

CONDITIONS

Official Title

Time to BBVNA Relief

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of chronic axial low back pain with vertebrogenic features
  • Scheduled for basivertebral nerve ablation
  • Able to provide informed consent
  • Able to participate in weekly virtual or phone follow-up for 8 weeks and in-person or remote follow-up visits at 3, 6, 12, and 24 months
Not Eligible

You will not qualify if you...

  • Prior spinal neuromodulation therapy within the past 6 months
  • Active substance use disorder or uncontrolled psychiatric illness that may interfere with participation
  • Cognitive impairment limiting ability to complete surveys or provide informed consent
  • Pregnancy
  • Incarceration or current prisoner status

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Yale Spine and Pain Center - Guilford

Guilford, Connecticut, United States, 06437

Actively Recruiting

2

Yale Pain Management Center - New Haven

New Haven, Connecticut, United States, 06519

Actively Recruiting

3

Yale Interventional Spine and Musculoskeletal Medicine - Old Saybrook

Old Saybrook, Connecticut, United States, 06475

Actively Recruiting

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Research Team

C

Charles A Odonkor, MD

CONTACT

M

Muhammad U Siddique, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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