Study of Time-Restricted Eating for Adults with Obesity to Evaluate Safety and Effectiveness Over 8 Weeks

What this Trial Is About

Researchers are evaluating time-restricted eating TRE in healthy, sedentary adults with obesity aged 19 to 65 years. This randomized controlled trial aims to understand how well participants follow TRE, its acceptability, and safety over 8 weeks. The study compares TRE with a non-fasting control group, focusing on calorie intake and adherence while also looking at hunger, cravings, body composition, diet quality, sleep, and overall well-being. Participants are randomly assigned to either the TRE group or the control group. The TRE group will consume calorie-containing foods and drinks within an 8-hour window each day between 6 a.m. and 8 p.m. and fast for the remaining 16 hours, while the control group will maintain their usual eating habits over 12 hours or more. The intervention lasts 8 weeks, following a baseline week, with some flexibility allowed for the eating window start and end times. During the study, participants will be monitored for adherence and calorie intake and assessed on body weight, body fat percentage, fat mass, muscle mass, physical activity, hunger and satiety, sleep quality, diet quality, perceptions of health, weight bias internalization, disordered eating risk, and skin carotenoid levels. Data will be collected at baseline, after 2 weeks, and at the end of the 8-week intervention. Participants should expect regular evaluations and questionnaires to track these outcomes throughout the 9-week study period.

Time-restricted Eating Acceptability, Efficacy and Safety in Obesity