Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
FEMALE
Healthy Volunteers
NCT06508255

Time-restricted Eating and Cognition

Led by German Institute of Human Nutrition · Updated on 2024-07-18

35

Participants Needed

1

Research Sites

41 weeks

Total Duration

On this page

Sponsors

G

German Institute of Human Nutrition

Lead Sponsor

P

Prof. Dr. Olga Ramich (German Institute of Human Nutrition)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to investigate how time-restricted eating (TRE), more specifically TRE at different times (early vs late in the day), influences brain activity, behavior, decision-making, food intake, physical activity, the gut microbiome and metabolic processes. The study intervention procedure is a replication of that described in Peters et al. (2021).

CONDITIONS

Official Title

Time-restricted Eating and Cognition

Who Can Participate

Age: 18Years - 70Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Right-handed
  • Legally competent
  • Physically and mentally healthy
  • Body Mass Index (BMI) between 19 and 35 kg/m²
  • Fluent in reading and speaking German
Not Eligible

You will not qualify if you...

  • Weight change greater than 5% of body weight in the last 3 months
  • Pregnancy or breastfeeding
  • Allergies (inclusion possible after consultation with study doctor)
  • History of cardiovascular disease (myocardial infarction, stroke, hypertension, hypotension) in the last year
  • Severe psychiatric condition, including drug addiction and depression
  • Impaired renal or liver function
  • Dementia or other severely debilitating cognitive disease
  • History of or current eating disorders (e.g., Bulimia nervosa, Anorexia nervosa, Orthorexia nervosa, Binge-Eating disorder)
  • Chronic diseases (e.g., Morbus Crohn, Colitis Ulcerosa)
  • Metabolic disorders (e.g., metabolic syndrome, diabetes type 1 or 2)
  • Hormonal imbalances (e.g., thyroid gland diseases)
  • Consuming diseases (e.g., cancer, cachexia) in the last 2 years
  • Surgical removal (partial removal) of digestive organs or history of bariatric surgery
  • Autoimmune conditions or current infection
  • Blood clotting disorders (e.g., haemophilia)
  • Severe anemia
  • Severe claustrophobia
  • Blood donation four weeks prior to study entry
  • Use of oral glucocorticoid therapy
  • Use of anticoagulant medication (inclusion possible if medication can be paused)
  • Taking medications that require regular eating
  • Any medications or supplements known to affect sleep, circadian rhythms, immune activity, or metabolism
  • Taking weight loss, lipid, or glucose-lowering medications (e.g., metformin)
  • Pacemaker or other electrical implant
  • Vaccination during the study or in the two weeks prior
  • Immunosuppressive premedication
  • Currently on a diet or fasting regime (or within 1 month)
  • Professional athletes
  • Nicotine consumption
  • Drug abuse
  • Alcohol consumption exceeding 14 beers (0.3l), wine (0.125l), sparkling wine (0.1l), or schnaps (4cl) per week
  • Shift work
  • Poor sleep quality (PSQI score greater than 10 at medical screening)
  • Travel across more than one time zone one month before or during the study
  • Non-removable metallic implants
  • Fear of blood draw

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

German Institute of Human Nutrition (DIfE)

Nuthetal, Germany

Actively Recruiting

Loading map...

Research Team

L

Lara Ryan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here