Study of Time Restricted Eating Effects on Metabolic and Cardiovascular Health in Adults With Obstructive Sleep Apnea

What this Trial Is About

Researchers are studying the effects of time restricted eating TRE on people with obstructive sleep apnea OSA, a condition linked to heart and metabolic problems like high blood pressure, diabetes, and obesity. While the current OSA treatment, continuous positive airway pressure CPAP, helps with blood pressure, it does not improve metabolic issues. This trial aims to see if limiting eating to a 10-hour daily window for 12 weeks can improve blood sugar control, cholesterol, sleep apnea severity, and quality of life compared to usual eating habits. Participants will be randomly assigned to either a TRE group, where they limit all calorie intake to a self-chosen 8-10 hour period each day for 12 weeks, or a standard eating group that continues their normal diet. Before the intervention, participants undergo a 2-week baseline period wearing a continuous glucose monitor and an activity watch while logging their food intake using a smartphone app. During the 12-week intervention, participants continue to track food and have biweekly virtual check-ins. At weeks 10 and 12, additional monitoring and assessments occur including sleep apnea testing and blood draws. Throughout the study, participants complete questionnaires, dietary recalls, blood tests, and wear devices to monitor glucose and activity. The study measures changes in daily glucose levels, LDL cholesterol, OSA severity, and quality of life after 12 weeks. Participants provide feedback on their experience, and researchers monitor adherence and safety. The study lasts about 14 weeks including baseline and intervention periods with ongoing support and data collection.

Time Restricted Eating in Sleep Apnea