Study of Time-Restricted Eating to Improve Pancreatic Function and Blood Sugar Control in Adults With Type 2 Diabetes and Overweight

What this Trial Is About

Researchers are studying time-restricted eating as a potential way to preserve pancreatic beta-cell function and improve blood sugar control in people with type 2 diabetes. This randomized controlled trial focuses on adults who have been diagnosed with type 2 diabetes within the last 10 years and have a body mass index BMI over 25. The study aims to evaluate whether limiting eating to a certain time window each day can help with metabolic health and diabetes management. Participants will be randomly assigned to one of two groups. One group will follow a time-restricted eating plan where they fast for 18 hours each day and eat only during a 6-hour window from 2 to 8 PM for 52 weeks. The other group will follow standard lifestyle recommendations based on Diabetes Canada guidelines, which encourage regular meal timing but do not specify fasting periods. Both groups will be monitored throughout the year-long study. During the study, participants will undergo assessments to measure their insulin secretion and sensitivity, insulin resistance, and the amount of time their blood sugar stays within target ranges. These measures will be compared between the two groups after 52 weeks. Participants weight stability, medication use, and adherence to the assigned eating plan will be tracked. Safety and metabolic health will be monitored throughout the trial, which is expected to continue until July 2029.

Time Restricted-EAting for Type 2 Diabetes and MEtabolic Health: the TEA TIME Trial