Study of Time-Restricted Feeding to Improve Metabolic Health in Postmenopausal Women Aged 45 to 65

What this Trial Is About

Researchers are evaluating how time-restricted feeding TRF affects metabolic risk in postmenopausal women aged 45 to 65 years who are metabolically unhealthy. This study aims to understand whether limiting the daily eating window can improve insulin sensitivity, glucose tolerance, body weight, and other metabolic markers. Postmenopausal women may be especially vulnerable to disruptions in circadian eating rhythms, which can worsen metabolic health. Participants are randomly assigned to one of two groups for 16 weeks a TRF group or a control group with no eating window restrictions. Those in the TRF group learn about TRF benefits and choose a 10-hour daily window to consume all their calories. Both groups track and report the timing of their first and last meals throughout the study. Baseline data on food timing, sleepactivity, and metabolic health are collected during the first two weeks before the intervention begins. Over the 18-week study, participants undergo assessments at baseline and after the intervention, including glucose tolerance tests, body composition measurements, weight and lipid panels, and inflammation markers. Sleep quality and timing are also monitored. These evaluations help researchers measure changes in insulin sensitivity, body mass index, triglycerides, and other health indicators. The study includes monitoring adherence to meal timing via daily text messages and collects comprehensive metabolic and physiological data to understand TRFs impact.

Circadian Rhythms in Postmenopausal Women