Actively Recruiting
Timing of Endoscopy in Cirrhotic Patients with Acute Variceal Bleeding
Led by General Hospital of Shenyang Military Region · Updated on 2025-02-27
368
Participants Needed
1
Research Sites
116 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Endoscopy is important for the diagnosis and treatment of acute upper gastrointestinal bleeding (AUGIB), especially acute variceal bleeding (AVB), in patients with liver cirrhosis. However, the optimal timing of endoscopy remains controversial, primarily because the currently available evidence is of poor quality, and the definition of early endoscopy is also very heterogeneous among studies. Herein, a multicenter randomized controlled trial (RCT) is performed to explore the impact of timing of endoscopy on the outcomes of cirrhotic patients with AVB.
CONDITIONS
Official Title
Timing of Endoscopy in Cirrhotic Patients with Acute Variceal Bleeding
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with acute upper gastrointestinal bleeding highly suspected to be caused by gastroesophageal variceal rupture
- Diagnosis of liver cirrhosis based on imaging and pathology
- Patients or their relatives who sign informed consent
- Age 18 years or older
You will not qualify if you...
- Patients who have had endoscopy at other hospitals before admission
- Patients with unstable hemodynamics after resuscitation
- Patients with severe cardiovascular, cerebrovascular diseases, or renal injury
- Patients who took anticoagulants or antiplatelet drugs within 2 weeks before admission or have severe blood disorders
- Patients with HIV or other acquired or congenital immune deficiency diseases
- Patients with mental illness
- Pregnant patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Gastroenterology, General Hospital of Northern Theater Command (formerly called General Hospital of Shenyang Military Area)
Shenyang, Liaoning, China
Actively Recruiting
Research Team
X
Xingshun Qi, MD
CONTACT
X
Xingshun Qi, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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