Actively Recruiting
Timing of Renal Replacement Therapy Initiation in Tumor Lysis Syndrome
Led by University Hospital, Bordeaux · Updated on 2026-01-09
800
Participants Needed
10
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The TENDERS study aims to evaluate the impact of the timing of renal replacement therapy (RRT) initiation on outcomes in patients with tumor lysis syndrome (TLS) and associated acute kidney injury (AKI). The study will compare early versus delayed RRT initiation, examining the effect on renal function at 30 days post-treatment.
CONDITIONS
Official Title
Timing of Renal Replacement Therapy Initiation in Tumor Lysis Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 618 years
- Hospitalized in the ICU between January 1, 2013, and December 31, 2023
- Diagnosed with a hematologic malignancy or solid tumor requiring chemotherapy
- Diagnosed with tumor lysis syndrome based on at least two biochemical criteria within 3 days before or 7 days after chemotherapy initiation (e.g., hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia)
You will not qualify if you...
- Patient or family opposition to data collection for research purposes
- Incomplete medical records that prevent data extraction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 10 locations
1
CHU d'Angers
Angers, France
Withdrawn
2
Hôpital Pellegrin
Bordeaux, France
Actively Recruiting
3
Hôpital la cavale blanche
Brest, France
Actively Recruiting
4
CHU Dupuytren 1
Limoges, France
Withdrawn
5
Hôtel-Dieu
Nantes, France
Actively Recruiting
6
CHR d'Orléans
Orléans, France
Actively Recruiting
7
CH de Pau
Pau, France
Actively Recruiting
8
Centre Urgences-Réanimations
Rennes, France
Actively Recruiting
9
IUCT-O Hopital Purpan
Toulouse, France
Actively Recruiting
10
Hôpital Bretonneau
Tours, France
Actively Recruiting
Research Team
A
Arthur ORIEUX
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here